Travel Award
As Editor-in-Chief of the Journal of Cardiovascular Development and Disease (JCDD), I am pleased to announce that the winner of the 2017 JCDD Travel Award, is Dr. Jae Gyun Oh, a Postdoctoral researcher in Prof. Roger J. Hajjar’s laboratory at Icahn School of Medicine at Mt Sinai, NY, USA, who will receive 800 Swiss Francs towards travel expenses to attend 2017 Keystone Symposia to be held in Keystone, CO, USA.
Dr. Oh’s current research focuses on the role of miR-146a as a SUMO1 targeting microRNA (miR). SUMO1 has been shown to be a critical player in heart failure (HF) pathophysiology. The expression of miR-146a shows an inverse correlation with SUMO1. In his project, Dr. Oh investigated which cell types contribute to miR-146a expression. He analyzed isolated myocyte and non-myocyte fractions from normal and failing hearts and determined that during HF, upregulation of miR-146a and downregulation of SUMO1 was confirmed in cardiomyocytes, but that the amount of pri-mir-146a indicating transcription of miR-146a was increased only in nonmyocytes.
He tested the hypothesis that cell-to-cell transfer of mature miR-146a can explain the increase in miR-146a in cardiomyocytes and found that miR-146a is mainly secreted from fibroblasts via exosomes and that these fibroblast exosomes are taken up by cardiomyocytes. The major conclusion of Dr. Oh’s research presented in his abstract for this meeting is that fibroblasts are a major source of miR-146a during HF, and exosome-mediated miR-146a transfer is a critical mechanism of cardiomyocyte function.
Dr. Oh’s current research focuses on the role of miR-146a as a SUMO1 targeting microRNA (miR). SUMO1 has been shown to be a critical player in heart failure (HF) pathophysiology. The expression of miR-146a shows an inverse correlation with SUMO1. In his project, Dr. Oh investigated which cell types contribute to miR-146a expression. He analyzed isolated myocyte and non-myocyte fractions from normal and failing hearts and determined that during HF, upregulation of miR-146a and downregulation of SUMO1 was confirmed in cardiomyocytes, but that the amount of pri-mir-146a indicating transcription of miR-146a was increased only in nonmyocytes.
He tested the hypothesis that cell-to-cell transfer of mature miR-146a can explain the increase in miR-146a in cardiomyocytes and found that miR-146a is mainly secreted from fibroblasts via exosomes and that these fibroblast exosomes are taken up by cardiomyocytes. The major conclusion of Dr. Oh’s research presented in his abstract for this meeting is that fibroblasts are a major source of miR-146a during HF, and exosome-mediated miR-146a transfer is a critical mechanism of cardiomyocyte function.
JCDD 2017 Travel Award
Past Winners
Year:
Winner
Junichi Saito
Yale University
Hannah Tarolli
Medical University of South Carolina
Award Committee
Prof. Dr. Thomas Brand
Chairman
Imperial College London, UK
Dr. Maria Grazia Andreassi
CNR Institute of Clinical Physiology, Italy
Prof. Dr. Paolo Emilio Puddu
Sapienza University of Rome, Italy
Dr. Óscar Lorenzo González
Universidad Autonoma de Madrid, Spain
Winner
Pengyu Zong
UConn John Dempsey Hospital Calhoun Cardiology Center, USA
Sandra Díaz del Moral
INSERM, France
Award Committee
Prof. Thomas Brand
Chairman
Imperial College London
Prof. Dr. Narayanaswamy Venketasubramanian
Raffles Neuroscience Centre, Raffles Hospital
Prof. Dr. Martin Schweiger
Pediatric Cardiovascular Surgery, Pediatric Heart Center, Department of Surgery, University Children’s Hospital Zurich
Prof. Paolo Emilio Puddu
Sapienza University of Rome
Winner
Cristiana Dondi
Sanford Burnham Prebys, USA
Tamara Gonzalez-Costa
Centro Nacional de Investigaciones Cardiovasculares, Spain
Award Committee
Dr. Maurice J B van den Hoff
Chairman
Department of Medical Biology
Dr. Glenn Fishman
NYU School of Medicine
Prof. Dr. giuseppe caminiti
S.Raffaele IRCCS Rome; San Raffaele Open University , 00163 Rome, Italy.
Prof. Antonino S Rubino
University of Enna Kore
Winner
Susanna Cooper
St. George's University of London, UK
Renée Tillie
Maastricht University Medical Center, The Netherlands
Award Committee
Prof. Andy Wessels
Chairman
medical university of south carolina
Dr. Maria Grazia Andreassi
CNR Institute of Clinical Physiology
Prof. Dr. Krzysztof J. Filipiak
Dr. Yeon Hyeon Choe
Prof. Fabio Angeli
Department of Medicine and Surgery, University of Insubria, Varese and Department of Medicine and Cardiopulmonary Rehabilitation, Maugeri Care and Research Institutes - IRCCS Tradate, Varese - Italy
Winner
Colette A. Bichsel
Boston Children’s Hospital, USA
Winner
Jae Gyun Oh
Icahn School of Medicine at Mount Sinai, USA
