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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Drug Repurposing: Emerging Approaches to Drug Discovery (2nd Edition)
edited by
submission deadline 30 Sep 2025 | Viewed by 37 | Submission Open
Keywords: repurposed drugs; network medicine; systems medicine; drug design; therapeutic strategies; drug repurposing in the era of artificial intelligence; drug repositioning; machine learning
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Microbiology in the Omics Era: Genomics, Metagenomics and Computational Insights
edited by
submission deadline 30 Sep 2025 | Viewed by 37 | Submission Open
Keywords: microbial genomics; metagenomics; computational biology; antimicrobial resistance; host– microbe interactions; multi-omics integration; bioinformatics tools; machine learning in microbiology
(This special issue belongs to the Section Molecular Microbiology)
Plant Senescence Under Environmental Stresses submission deadline 30 Sep 2025 | Viewed by 37 | Submission Open
Keywords: plant senescence; environmental stresses; phytohormones
(This special issue belongs to the Section Molecular Plant Sciences)
Pesticide Exposure and Toxicity Research: Impacts on Endocrine and Nervous System Pathophysiology
edited by
submission deadline 30 Sep 2025 | Viewed by 36 | Submission Open
Keywords: pesticide exposure; neurotoxicity; endocrine disruption; risk assessment; toxicological mechanisms; human health effects; biomonitoring; animal models
(This special issue belongs to the Section Molecular Toxicology)
Molecular Biology of Periodontal Disease and Periodontal Pathogens
edited by Yago Leira and
submission deadline 30 Sep 2025 | Viewed by 36 | Submission Open
Keywords: periodontitis; general medicine; inflammation; bacteraemia; education
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Bioplastic-Related Toxicity in Humans: New Insights and Molecular Mechanisms submission deadline 30 Sep 2025 | Viewed by 36 | Submission Open
Keywords: bioplastics and biopolymers -related toxicity; microplastics and nanoplastics accumulation/degradation in mammals; cell cultures; human health; in vivo models; epigenetics effects; endocrine disruptor properties of bioplastics; bioplastics and inflammation; bioplastics in neurodegeneration and neuroinflammation; reproduction; cell metabolism; immunomodulation
(This special issue belongs to the Section Molecular Toxicology)
Advances in Plant Biotechnology: From Pathogen Diagnostics to Disease Management submission deadline 30 Sep 2025 | Viewed by 35 | Submission Open
Keywords: plant pathogens; diagnostic; isothermal; biosensor; RNAi; CRISPRi; QTL mapping; GWAS; MAS or MABC
(This special issue belongs to the Section Molecular Plant Sciences)
Research on System Biology Methods and Tools for Integrating Omics Data
edited by Yuanyan Xiong
submission deadline 30 Sep 2025 | Viewed by 35 | Submission Open
Keywords: systems biology; multi-omics integration; network analysis; computational biology; bioinformatics tools; machine learning; precision medicine
(This special issue belongs to the Section Molecular Informatics)
Plant Breeding Strategies: Employment of Plant Adaptation Mechanisms to Biotic and Abiotic Stresses
edited by
submission deadline 30 Sep 2025 | Viewed by 34 | Submission Open
Keywords: marker-assisted selection; molecular breeding; whole-transcriptome analysis; RNA sequencing; DNA sequencing; plant stress response
(This special issue belongs to the Section Molecular Plant Sciences)
Bone Microenvironment and Bone Metastasis submission deadline 30 Sep 2025 | Viewed by 34 | Submission Open
Keywords: bone metastasis; tumor– bone interaction; bone microenvironment; osteoclastogenesis; osteoblast signaling; bone remodeling; dormancy; immune evasion; extracellular matrix
(This special issue belongs to the Section Molecular Oncology)
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