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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Drug Delivery Systems: From Nanocarrier Design to Translation submission deadline 31 May 2027 | Viewed by 115 | Submission Open
Keywords: nanocarriers; stimuli-responsive; targeted delivery; biocompatibility; scale-up; nanomedicine
(This special issue belongs to the Section Materials Science)
Molecular Mechanisms Linking Environmental Pollutant Exposure to Human Health and Development
edited by Agnieszka Ścibior and
submission deadline 31 May 2027 | Viewed by 74 | Submission Open
Keywords: environmental pollutants; molecular toxicology; developmental toxicology; particulate matter; metals and metalloids; pesticides; persistent organic pollutants; PFAS; environmental pharmaceuticals; microplastics; nanoplastics; mixture toxicity; adverse outcome pathways; human biomonitoring; toxicokinetics; oxidative stress; genotoxicity; epigenetics; endocrine disruption; neurodevelopment; human health risk assessment
(This special issue belongs to the Section Molecular Toxicology)
Functional Polymeric Biomaterials: From Molecular Engineering to Biomedical Applications submission deadline 1 Jun 2027 | Viewed by 38 | Submission Open
Keywords: polymeric biomaterials; biodegradable polymers; molecular design; AI-driven materials design; structure–property relationships; biomolecule–material interactions; biocompatibility; drug delivery systems; tissue engineering; regenerative medicine
(This special issue belongs to the Section Materials Science)
The Chitosan Biomaterials: Advances and Challenges, 3rd Edition
edited by , and Cristina Elena Dinu-Pirvu
submission deadline 20 Jun 2027 | 1 articles | Viewed by 1595 | Submission Open
Keywords: chitosan; chitosan biomaterials; chitosan derivatives; drug delivery; wound healing; tissue regeneration; dentistry; smart biomaterials
(This special issue belongs to the Section Materials Science)
Molecular Progression of Genome-Related Diseases: 2nd Edition
edited by
submission deadline 25 Jun 2027 | 6 articles | Viewed by 22147 | Submission Open
Keywords: next-generation sequencing; genetic diseases; multifactorial diseases; diagnostic tolls; human health
(This special issue belongs to the Section Molecular Genetics and Genomics)
Effects of Bioactive Compounds in Cardiovascular and Neurological Diseases submission deadline 30 Jun 2027 | 1 articles | Viewed by 2734 | Submission Open
Keywords: inflammation; oxidative stress; bioactive compounds; cardiovascular diseases; neurological diseases
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Targeting Oxidative Stress: New Insights into Disease Pathogenesis, Emerging Preventive Strategies and Novel Therapeutic Approaches
edited by Fabio Vivarelli and
submission deadline 30 Jun 2027 | 2 articles | Viewed by 2184 | Submission Open
Keywords: metabolism; inflammation; oxidative stress; diabetes; natural oxidative stress modulators; novel preventive/therapeutic strategies; ageing; cardiovascular diseases; regenerative medicine; neurodegeneration; environmental exposure; cancer
(This special issue belongs to the Section Molecular Biology)
From Molecular Understanding to Ecological Significance: Understanding Marine Reproductive Biology
edited by
submission deadline 30 Jun 2027 | Viewed by 434 | Submission Open
Keywords: reproductive biology; gametogenesis; bivalves reproduction; biodiversity; endocrine regulation; gametogenesis; molecular signaling; genomics; fertilization; population dynamics; ecological resilience
(This special issue belongs to the Section Molecular Biology)
Sex and Gender Medicine: New Horizons in Human Health and Disease
edited by , Eliana Ferroni and
submission deadline 30 Jun 2027 | 1 articles | Viewed by 140 | Submission Open
Keywords: sex differences; gender medicine; personalized medicine; health inequities; intersectionality; precision health
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Nanoparticle Toxicity: Beyond Chemical Composition—the Critical Role of Physicochemical Properties
edited by
submission deadline 31 Jul 2027 | 1 articles | Viewed by 1201 | Submission Open
Keywords: nanotoxicology; engineered nanomaterials; physicochemical properties; risk assessment; reactive oxygen species (ROS); protein corona; cellular uptake; regulatory science; safe-by-design
(This special issue belongs to the Section Molecular Toxicology)
Selected Papers from the HSG-2025 Conference
edited by
submission deadline 31 Jul 2027 | 1 articles | Viewed by 855 | Submission Open
Keywords: metagenomics; genomics; metabarcoding; next-generation sequencing; transcriptomics; translatomics; NGS data analysis
(This special issue belongs to the Section Molecular Genetics and Genomics)
Machine Learning in RNA and Chromatin Dynamics
edited by Haopeng Yu
submission deadline 31 Jul 2027 | Viewed by 554 | Submission Open
Keywords: machine learning; chromatin architecture; RNA dynamics; genomic foundation models; computational biology
(This special issue belongs to the Section Molecular Biology)
Molecular Research on Aging: Genetics, Epigenetics and Biomolecular Interventions
edited by
submission deadline 31 Jul 2027 | Viewed by 29 | Submission Open
Keywords: aging; biomarkers; bioactive nutrients; centenarians; life-extending interventions; exercise; red wine; stress resistance and metabolism; age-related diseases
(This special issue belongs to the Section Molecular Biology)
Exploring Molecular Mechanisms of Neuroendocrine Tumors
edited by and Michele Ghidini
submission deadline 31 Jul 2027 | Viewed by 13 | Submission Open
Keywords: rare tumours; neuroendocrine neoplasms; translational research; gut microbiome; liquid biopsy; novel targets; VHL1; predictive biomarkers; tumour microenvironment
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Bioinformatics Analysis of Single Cell and Spatial Multi-Omics
edited by Fahong Yu
submission deadline 20 Aug 2027 | 1 articles | Viewed by 1243 | Submission Open
Keywords: bioinformatics; single-cell omics; spatial multi-omics; matabolomics; genomics; transcriptomics; proteomics; next-generation sequencing techniques
(This special issue belongs to the Section Molecular Informatics)
Molecular Mechanisms, Biomarkers, and Translational Research in Stroke and Neurotrauma
edited by Kang-Ho Choi
submission deadline 30 Aug 2027 | Viewed by 7 | Submission Open
Keywords: stroke; cerebrovascular disease; endovascular thrombectomy; prognostic biomarkers; molecular pathophysiology; neurovascular imaging; lipidomic metabolites; experimental neurology; clinical trial methodologies; novel therapeutic approaches
(This special issue belongs to the Section Molecular Neurobiology)
Research on Genomics of Crop Stress Tolerance
edited by
submission deadline 31 Aug 2027 | 2 articles | Viewed by 876 | Submission Open
Keywords: crop stress tolerance; genomic research; molecular mechanisms; multi-omics approaches; epigenetic modifications
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Targeting in Nanoparticle Systems: Precision Therapy, Detoxification, and Environmental Remediation
edited by and Dan Eduard Mihəiescu
submission deadline 31 Aug 2027 | Viewed by 420 | Submission Open
Keywords: nanoparticles; nanocomposites; molecular targeting; stimuli-responsive materials; magnetic nanoparticles; surface functionalization; precision therapy; detoxification; decontamination; environmental remediation
(This special issue belongs to the Section Molecular Nanoscience)
Advances in Molecular and Cellular Biology in Neuroscience
edited by
submission deadline 31 Aug 2027 | Viewed by 171 | Submission Open
Keywords: molecular neuroscience; cellular neurobiology; imaging; synaptic plasticity; optogenetics; brain visualization; signal transduction; developmental molecular and cellular biology in neuroscience; neurological disorders
(This special issue belongs to the Section Molecular Neurobiology)
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