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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Lipopolysaccharide as a Drug Target
edited by
submission deadline 20 Aug 2026 | Viewed by 141 | Submission Open
Keywords: tissue barriers; neuroinflammation; macrophages; microglia; organoids; scaffolds; infections; cry-EM
(This special issue belongs to the Section Molecular Pharmacology)
Vitamin D in Reproductive Disorders: Determinants, Metabolism, and Downstream Biological Mechanisms submission deadline 20 Aug 2026 | Viewed by 85 | Submission Open
Keywords: vitamin D; perinatal corticosteroids; placental insufficiency; intrauterine growth restriction; cortisol metabolism
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Effects of Radiation in Health and Disease submission deadline 20 Aug 2026 | Viewed by 14 | Submission Open
Keywords: extremely low-frequency magnetic fields; proteins and gene interaction; ionizing and non-ionizing radiations
(This special issue belongs to the Section Molecular Biology)
Current Research on Lipidomics
edited by Agata Kot-Wasik
submission deadline 25 Aug 2026 | Viewed by 14 | Submission Open
Keywords: lipids  ; hyphenated chromatography– mass spectrometry  ; biological samples  ; sample preparation
(This special issue belongs to the Section Molecular Biology)
Neurotransmitter Dysregulation in Brain Disease: Focus on Epilepsy and Its Comorbidities submission deadline 30 Aug 2026 | Viewed by 91 | Submission Open
Keywords: neurotransmitter dysregulation; epilepsy; addiction; serotonin; GABA; molecular neuroscience; neuropharmacology; brain networks
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Mechanisms Fueling Glioblastoma Progression and Resistance: Emerging Therapeutic Opportunities
edited by
submission deadline 30 Aug 2026 | Viewed by 55 | Submission Open
Keywords: glioblastoma; cancer stem cells; radioresistance; chemoresistance; targeted therapies; tumor plasticity; tumor heterogeneity; invasion; immune escape
(This special issue belongs to the Section Molecular Neurobiology)
MiRNA Stromal Interaction in the Tumor Microenvironment
edited by
submission deadline 30 Aug 2026 | Viewed by 39 | Submission Open
Keywords: microRNAs; early tumor microenvironment (TME); stromal/ECM interaction; vascularization; ECM remodelling; signalling pathways
(This special issue belongs to the Section Molecular Oncology)
Biomarkers and Early Detection Strategies of Ovarian Tumors: 2nd Edition
edited by Lukasz Szafron
submission deadline 30 Aug 2026 | Viewed by 2 | Submission Open
Keywords: biomarker; ovarian cancer; borderline ovarian tumor; genetic variant; epigenetics; transciptomics; proteomics; metabolomics; ovarian tumor prevention; ovarian tumor treatment
(This special issue belongs to the Section Molecular Oncology)
Latest Advances in Antiparasitic Agents
edited by Olga S. Koutsoni and
submission deadline 30 Aug 2026 | Viewed by 1 | Submission Open
Keywords: parasite genomics; parasite proteomics; metabolic pathways; parasite– host interactions; drug targets; mechanisms of drug resistance
(This special issue belongs to the Section Molecular Pharmacology)
The Role of Neuropeptides and Their GPCRs in the Neuroendocrine System
edited by
submission deadline 31 Aug 2026 | Viewed by 545 | Submission Open
Keywords: neuropeptides; G-protein-coupled receptors (GPCRs); neuroendocrine system; signal transduction; hypothalamus
(This special issue belongs to the Section Molecular Neurobiology)
Animal Models for Neurobiological Diseases submission deadline 31 Aug 2026 | Viewed by 2 | Submission Open
Keywords: animal models; mice; zebrafish; Alzheimer's disease; Parkinson's disease; multiple sclerosis; neuropsychiatric conditions
(This special issue belongs to the Section Molecular Neurobiology)
Advanced Research in Veterinary Drugs
edited by Jianyong Li
submission deadline 20 Sep 2026 | 1 articles | Viewed by 1641 | Submission Open
Keywords: veterinary drug; target; chemical structure; mechanism; medicinal chemistry; toxicity; pharmacodynamics; pharmacokinetics; residues
(This special issue belongs to the Section Molecular Pharmacology)
Exopolysaccharides of Microbial Origin: Production, Analysis and Modification
edited by Marzena Jedrzejczak-Krzepkowska and
submission deadline 20 Sep 2026 | Viewed by 60 | Submission Open
Keywords: exopolysaccharide; biopolymer; biofilm; microorganism; biosynthesis; genetic engineering; molecular design; modification; analysis
(This special issue belongs to the Section Molecular Microbiology)
Molecular Research on Tea Flavor and Chemistry
edited by
submission deadline 29 Sep 2026 | Viewed by 59 | Submission Open
Keywords: tea processing; tea chemistry; tea functional components; tea sensory evaluation; tea quality control
(This special issue belongs to the Section Biochemistry)
Molecular Mechanisms in Forensic Pathology
edited by
submission deadline 29 Sep 2026 | Viewed by 21 | Submission Open
Keywords: molecular investigation; molecular thanatocronology; molecular autopsy; lesion vitality; molecu-lar forensic toxicology; pharmacogenomics; molecular identification
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Genetic, Functional and Therapeutic Aspects of Procoagulant and Anticoagulant Factors (Third Edition)
edited by and
submission deadline 30 Sep 2026 | 1 articles | Viewed by 745 | Submission Open
Keywords: procoagulant factors; anticoagulant factors; hemostasis; inflammation; genetics; therapeutics; cell signaling
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Phytochemical Insights and Green Extraction Strategies for Bioactive Natural Compounds submission deadline 30 Sep 2026 | Viewed by 144 | Submission Open
Keywords: plant and algal bioactive metabolites; phytochemistry; green extraction techniques; natural sustainable solvents (NADES); structural elucidation of natural molecules; molecular characterization
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Mechanism, Pathogenesis, and Precision Therapeutics in Thyroid Cancer
edited by
submission deadline 30 Sep 2026 | Viewed by 32 | Submission Open
Keywords: thyroid cancer; molecular pathogenesis; driver mutations; tumor microenvironment; targeted therapy; resistance mechanisms; immunotherapy; precision oncology; liquid biopsy; prognostic biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advance in Plant Abiotic Stress: 4th Edition
edited by and
submission deadline 30 Oct 2026 | 1 articles | Viewed by 478 | Submission Open
Keywords: abiotic stress; cold; drought; salt; heat; nutrient deficiency; secondary metabolism; stress resistance; plant
(This special issue belongs to the Section Molecular Plant Sciences)
Precision Photosynthesis: Mechanisms and Applications in Controlled Environments
edited by
submission deadline 30 Oct 2026 | Viewed by 11 | Submission Open
Keywords: controlled environment agriculture (CEA); photobioreactor; plant growth chamber; light-emitting diode (LED) spectrum; photosynthetic efficiency; acclimation; synthetic biology; metabolic engineering; high-throughput phenotyping; predictive modeling; vertical farming
(This special issue belongs to the Section Molecular Plant Sciences)
Organ Axis: Insights from Molecular Metabolism
edited by
submission deadline 31 Oct 2026 | Viewed by 2 | Submission Open
Keywords: organ axis; molecular metabolism; interorgan crosstalk; metabolic regulation; metabolic diseases; biomarkers; molecular pathways; metabolites
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Mechanisms and Emerging Therapies in Neurovascular Disease
edited by Leonidas D. Panos
submission deadline 20 Nov 2026 | 3 articles | Viewed by 11952 | Submission Open
Keywords: neurovascular diseases; blood– brain barrier; endothelial dysfunction; cellular signaling; gene therapy
(This special issue belongs to the Section Molecular Neurobiology)
Biomolecular Condensates and Their Role in Cellular Organization and Disease
edited by Anna Bratek-Skicki
submission deadline 20 Nov 2026 | Viewed by 616 | Submission Open
Keywords: biocondensates; membrane-less organelles; liquid-liquid phase separation; protein aggregation; neurogenerative diseases
(This special issue belongs to the Section Molecular Biology)
Bioactives in Processed Foods: Profiling and Bioavailability Assessment
edited by Cong Wang
submission deadline 20 Nov 2026 | Viewed by 230 | Submission Open
Keywords: food processing; food bioactives; composition; bioavailability; functionality; novel food processing techniques; structure/constituents– bioactivity relationship
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Research Progress on Disease Models Based on Induced Pluripotent Stem Cells submission deadline 30 Dec 2026 | Viewed by 58 | Submission Open
Keywords: induced pluripotent stem cells; iPSC-derived cells; disease modeling; precision and regenerative medicine; genome editing; CRISP/Cas; organoid; cell sheet; personalized therapeutics; drug discovery
(This special issue belongs to the Section Molecular Biology)
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