Special Issue "Dissecting the Purinergic Signaling Puzzle"
Deadline for manuscript submissions: closed (30 June 2020).
Interests: purinergic signaling; P2X receptors; P2Y receptors; neuroprotection; neural cells; protein phosphatases; DUSPs; signaling cascades
Interests: purinergic signaling; P2X receptors; P2Y receptors; neuroprotection; astrocytes; neural cells; protein phosphatases; DUSPs; signaling cascades
Purinergic signaling represents an expanding field involved in the regulation of a plethora of physio-pathological processes in different tissues and systems. One interesting feature that characterizes the purinergic network and makes it more complex and interesting than the rest of neurotransmitter systems is the numerous components integrating into a multistep cascade called “purinome”. In order to better understand the physiological relevance of nucleotide signaling, it should be considered as a whole, having an integrative view of all these elements and their relationships. The purinergic system includes nucleotide and adenosine receptors, and enzymatic and transporter activities interconverting nucleotides and nucleosides and connecting the intra- and extracellular spaces to regulate purinergic messenger availability. The aim of this Special Issue is to cover different key components of the purinergic system, regarding how they interact and work together in a coordinate fashion to shape and modulate the final biological response.
Prof. Raquel Pérez-Sen
Prof. Esmerilda G. Delicado
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- purinergic signaling
- P2X receptor
- P2Y receptor
- adenosine receptor
- adenosine/nucleoside transporter
- vesicular nucleotide transporter (VNUT)
- nucleotide/nucleoside metabolism
- intracellular pathways