Special Issue "Dissecting the Purinergic Signaling Puzzle"
Deadline for manuscript submissions: closed (30 November 2020).
Interests: purinergic signaling; P2X receptors; P2Y receptors; neuroprotection; neural cells; protein phosphatases; DUSPs; signaling cascades
Interests: purinergic signaling; P2X receptors; P2Y receptors; neuroprotection; astrocytes; neural cells; protein phosphatases; DUSPs; signaling cascades
Purinergic signaling represents an expanding field involved in the regulation of a plethora of physio-pathological processes in different tissues and systems. One interesting feature that characterizes the purinergic network and makes it more complex and interesting than the rest of neurotransmitter systems is the numerous components integrating into a multistep cascade called “purinome”. In order to better understand the physiological relevance of nucleotide signaling, it should be considered as a whole, having an integrative view of all these elements and their relationships. The purinergic system includes nucleotide and adenosine receptors, and enzymatic and transporter activities interconverting nucleotides and nucleosides and connecting the intra- and extracellular spaces to regulate purinergic messenger availability. The aim of this Special Issue is to cover different key components of the purinergic system, regarding how they interact and work together in a coordinate fashion to shape and modulate the final biological response.
Prof. Raquel Pérez-Sen
Prof. Esmerilda G. Delicado
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- purinergic signaling
- P2X receptor
- P2Y receptor
- adenosine receptor
- adenosine/nucleoside transporter
- vesicular nucleotide transporter (VNUT)
- nucleotide/nucleoside metabolism
- intracellular pathways