Nutraceuticals in the Prevention and Treatment of Inflammatory Diseases

Dear Colleagues,

Inflammatory diseases include a vast range of conditions and disorders that are orchestrated by chronic inflammation. Examples of inflammatory diseases include atherosclerosis, diabetes, obesity, rheumatoid arthritis and cancer. Such inflammatory diseases are responsible for most global deaths and therefore represent an enormous economic burden. Although pharmaceutical therapies have recently reduced morbidity and mortality from such inflammatory diseases, they are not fully effective and are associated with adverse side effects in some cases, thereby necessitating further research on alternative therapeutic avenues. Nutraceuticals, food products with health benefits beyond their nutritional values, represent promising alternatives for the prevention and treatment of inflammatory disorders. Studies aimed at underpinning the molecular mechanisms underlying nutraceutical actions together with large clinical trials are essential to fully realise their potential as preventative and therapeutic agents against inflammatory disorders.

This Special Issue is focused on nutraceuticals in the prevention and treatment of inflammatory diseases and will include original articles and reviews on mechanism-based in vitro and in vivo studies aimed at understanding the molecular mechanisms that underpin nutraceutical actions together with human studies aimed at delineating their efficacy as preventative and therapeutic agents. Potential topics include, but are not limited to, nutraceutical actions in cultured cells, animal models of inflammatory disorders and human subjects addressing aspects such as cellular responses, signal transduction, gene expression, intracellular targets, biomarkers and disease severity, bioavailability and several others.

Prof. Dr. Dipak Ramji
Guest Editor

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