Advance in Neurotoxicity Research from Development to Aging

Dear Colleagues,

A substance capable of inducing a consistent pattern of neural dysfunction or change in the chemistry or structure of the nervous system may be defined as neurotoxic. Even brief exposure to multiple substances can result in severe functional deficits, including abnormalities in relevant biochemical parameters, EEG findings, psychological and behavioral testing, neurological examinations, and axonopathy and cell death. The neurotoxins produce various effects in development and aging.

This Special Issue on the lifetime effects of neurotoxins on brain functioning will present new advances on some of the most common agents known to affect neural organization. Despite a growing body of preclinical studies demonstrating neurotoxic effects in both the developing and aging brain, the impact of neurotoxic agents on the human brain remains to be clarified. In particular, elderly subjects are at increased risk for adverse reactions given their physiological alterations that affect pharmacokinetic processes. 

This Special Issue welcomes papers addressing the different effects that exposure to neurotoxic agents may elicit in both developmental and aging stages.

Dr. Debora Cutuli
Dr. Laura Petrosini
Prof. Dr. Francesca Gelfo
Guest Editors

Manuscript Submission Information

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