Cell Colonization in Scaffolds
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (31 August 2018) | Viewed by 95820
Special Issue Editor
Interests: tissue engineering; biomedical engineering; biotechnology; microbiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Over the past 30 years, dramatic advances and technological developments have been made in Tissue Engineering and Regenerative Medicine (TE&RM), and a variety of engineered tissues or organs have been produced through proof-of-concept (PoC) studies. In order to overcome the current limitations related to the shortage of donated tissues/organs, it is necessary to further advance these PoC level studies to manufacture fully functional tissues or organs in a cost-effective way while ensuring good laboratory and manufacturing practice. However, this translational task is hindered by the lack of mechanistic understanding of tissue formation and relevant bioprocessing knowledge. This is because TE&RM strategies inherently recognise and incorporate the relationships between molecules, cells, tissues, organs and even the body as a whole, thus sufficient understanding of these relationships at different levels and the underpinning complex biological processes is the prerequisite for the reconstruction of tissues or organs.
The aim of this Special Issue is to introduce the recent advances in the basic and translational research of cell colonization in scaffolds. We invite authors to submit original research and review articles related to the design, fabrication and utilization of new or traditional biomaterials, scale-down and scale-up cell/tissue culture systems, cell/tissue imaging technologies and computational models for the mechanistic insights of cell–cell and cell–scaffold interactions during the formation of engineered tissues. We are particularly interested in articles that distinguish and investigate the regulatory functions of architectural, biochemical and biomechanical properties coexisted in different biomaterials or scaffolds on the cultivated cells through interdisciplinary approaches.
Dr. Sun Tao
Guest Editor
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Keywords
- Biomaterials
- Scaffold
- Cell culture
- Tissue culture
- Cell colonization
- Bioreactor development
- Cell/tissue imaging
- Computational of cells/tissues
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