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Molecular Biology of Cancer—Implications for Diagnosis and Treatment: 4th Edition

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".

Deadline for manuscript submissions: 30 January 2027 | Viewed by 22

Special Issue Editors


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Guest Editor
1. Faculty of Medicine, School of Health Sciences, University of Ioannina, 45 110 Ioannina, Greece
2. Department of Medical Oncology, University Hospital of Ioannina, 45 500 Ioannina, Greece
3. Faculty of Medicine, Health and Social Care, Canterbury Christ Church University, Canterbury, UK
4. School of Cancer and Pharmaceutical Sciences, King’s College London, London, UK
Interests: ovarian cancer; cervical cancer; prostate cancer; colorectal cancer; cancer in pregnancy; homologous recombination of DNA; PARP inhibitors
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Guest Editor
Department of Medical, Oral and Biotechnological Sciences, University of Chieti–Pescara, Chieti, Italy
Interests: cancer research; molecular biology; cell biology; pharmacology; drug discovery; photobiomodulation
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Special Issue Information

Dear Colleagues,

Cancer remains a major global health challenge and one of the leading causes of mortality worldwide. Despite remarkable advances in prevention, diagnosis, and treatment, the biological complexity of cancer continues to hinder the development of effective and durable therapeutic strategies. Over the past decades, significant progress in molecular biology has revealed the intricate genetic, epigenetic, transcriptomic, proteomic, and metabolic alterations that drive tumor initiation, progression, metastasis, and therapeutic resistance. A deeper understanding of these mechanisms is essential for the identification of novel biomarkers and the development of personalized approaches to cancer management.

This Special Issue, ‘Molecular Biology of Cancer—Implications for Diagnosis and Treatment: 4th Edition’, aims to provide an updated overview of recent advances in cancer biology and their translational implications. We welcome the submission of original research articles, reviews, and systematic studies that investigate the molecular mechanisms underlying cancer development and progression, as well as the innovative diagnostic and therapeutic strategies arising from these discoveries.

Particular emphasis will be placed on studies that explore tumor heterogeneity, cancer metabolism, tumor–microenvironment interactions, immune regulation, mechanisms of treatment resistance, and the identification of clinically relevant biomarkers. Contributions that employ emerging technologies, including next-generation sequencing, single-cell and spatial analyses, computational pathology, artificial intelligence, and multi-omics approaches, are especially encouraged.

Potential topics of interest for this Special Issue include the following:

  • Molecular mechanisms of carcinogenesis and tumor progression;
  • Cancer genomics, epigenomics, and transcriptomics;
  • Tumor microenvironment and cancer–immune system interactions;
  • Cancer metabolism and metabolic reprogramming;
  • Biomarker discovery for diagnosis, prognosis, and treatment response;
  • Mechanisms of drug resistance and therapeutic failure;
  • Precision oncology and personalized medicine;
  • Computational pathology and artificial intelligence in cancer research;
  • Multi-omics approaches for cancer characterization;
  • Novel molecular targets and emerging anticancer therapies.

We look forward to receiving your contributions and to advancing our understanding of cancer biology for improved patient diagnosis and treatment.

1st edition of the Special Issue “Molecular Biology of Cancer—Implications for Diagnosis and Treatment
2nd edition of the Special Issue “Molecular Biology of Cancer—Implications for Diagnosis and Treatment: 2nd Edition”
3rd edition of the Special Issue “Molecular Biology of Cancer—Implications for Diagnosis and Treatment: 3rd Edition”

Prof. Dr. Stergios Boussios
Dr. Tania Vanessa Pierfelice
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cancer molecular biology
  • tumor microenvironment
  • cancer biomarkers
  • precision oncology
  • cancer metabolism
  • translational cancer research

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