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Special Issue "Parkinson's Disease and Related Disorders: Mechanisms, Biomarkers, and Models"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 15 September 2021.

Special Issue Editors

Dr. Birgitt Schuele
E-Mail Website
Guest Editor
Department Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Interests: Parkinson's disease; genetics; stem cell modelling; neurodegeneration
Dr. Laurie Sanders
E-Mail Website
Guest Editor
Department of Neurology, Duke University School of Medicine, Durham, NC 27701, USA
Interests: Parkinson's disease; mitochondrial DNA damage; repair and bioenergetics

Special Issue Information

Dear Colleagues,

We are delighted to announce a call for submissions to a Special Issue of the International Journal of Molecular Sciences on the topic of “Parkinson's Disease and Related Disorders: Mechanisms, Biomarkers, and Models”.

Is Parkinson’s disease one big puzzle, or are we looking at many rare diseases under one umbrella?

This Special Issue offers an open access forum that is gathering a collection of review and primary research articles aiming to update and advance the current knowledge on PD mechanisms, biomarkers, and models, which also include genetic forms of PD.

The suggested potential topics include, but are not restricted to, mechanisms of mitochondrial dysfunction, lysosomal and proteasome failure, neuroinflammation, protein misfolding, calcium imbalance, synaptic dysfunction, oxidative stress, mitophagy, propagation, and spreading in the context of Parkinson’s disease and related neurodegenerative diseases. We also welcome contributions that shed light on pathologies overlapping with other neurodegenerative diseases, e.g., tau, amyloid, and TDP-43 accumulation. All model systems are of interest including flies, worms, fish models, rodent models (transgenic, pharmacological, viral, pre-formed fibrils), and nonhuman primates. All submitted articles will undergo peer review.

Dr. Birgitt Schuele
Dr. Laurie Sanders
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Neurodegeneration
  • Parkinson’s disease
  • Genetics/genomics
  • Mechanisms of neurodegeneration
  • Co-neuropathologies
  • Model organisms

Published Papers

This special issue is now open for submission.
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