Metal-Organic and Organometallic Compounds Targeting Intracellular Components Inducing Apoptosis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (30 May 2023) | Viewed by 4201
Special Issue Editors
Interests: crystal structure; structure determination; material characterization; structural chemistry; biological inorganic chemistry, antimicrobial compounds; antiproliferative compounds
Special Issues, Collections and Topics in MDPI journals
Interests: biological inorganic chemistry; anticancer metallodrugs; antibacterial metallodrugs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue of the journal IJMS entitled “Metal-organic and organometallic compounds targeting intracellular components inducing apoptosis" will cover a selection of recent research and review articles in the field of the development of new targeted metallodrugs for cancer chemotherapy.
The development of novel metallo-drugs by targeting specific intracellular biomolecules (proteins, DNA, etc.) or intracellular organelles (mitochondrion, membranes, etc.) is a new strategy for new chemotherapeutics designing with high selectivity and low side effects. For this, the understanding of how metal-based compounds interact with and affect cellular systems is important. The effects of the potential metallo-drugs on cellular signal-transduction pathways, elucidates the mechanism of apoptosis induction in cells.
The research in this field brings together stakeholders from different disciplines, including chemists, biologists, pharmacists, etc. The reader of this Special Issue will gain an appreciation of the real role of metal-organic and organometallic compounds targeting intracellular components inducing apoptosis.
Prof. Dr. Sotiris K Hadjikakou
Dr. Christina N. Banti
Guest Editors
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