Cellular and Molecular Mechanisms in Lung Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 June 2025 | Viewed by 2171
Special Issue Editor
Interests: cell biology of the lung and heart; organ protection; signaling transduction in the lung; experimental anesthesiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The lung, as the central organ of the respiratory system, functions to exchange oxygen from the inhaled air for carbon dioxide, an asphyxiant waste product of the metabolism.
Due to this crucial function, diseases of the lung have a severe impact on the wellbeing and are frequently even life-threatening, requiring mechanical ventilation or extracorporeal membrane oxygenation (ECMO). Pathologies of the respiratory system can be grouped into airway disease (asthma, chronic obstructive pulmonary disease (COPD), bronchiolitis, etc.), tissue disease (fibrosis, inflammation, sarcoidosis, cancer, etc.), or circulation disease affecting the blood vessels (clotting, inflammation, etc.), triggered by inhalation of toxic substances, viral, bacterial, or fungal infections, or other organs’ malfunction. Severe pulmonary conditions, such as acute respiratory distress syndrome (ARDS), are frequently still difficult to treat; therefore, progress in the understanding of molecular mechanisms is demanded. Lung cells of epithelial, endothelial, stromal, or immune cell types were found to be very heterogenous by themselves. This fact complicates mechanistic studies, but methodology and analysis techniques also make rapid progress to tackle this challenge.
As the Guest Editor of this Special Issue, I would like to invite authors working in this field to contribute their original work, along with review articles, that enhance our understanding of the status quo of research on molecular mechanisms and cellular function in the healthy or diseased, preferably human, but also rodent, lung.
Dr. Verena Tretter
Guest Editor
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Keywords
- lung disease
- asthma, chronic obstructive pulmonary disease
- fibrosis, inflammation, sarcoidosis
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