Association of Gut Microbiome and Food Allergies by –Omics Strategies

Dear Colleagues,

The global prevalence of food allergies (FA) has grown dramatically in recent years. The development of FA is directly related to several events and lifestyle changes that affect the gut microbiota composition and other factors, such as cesarean, antibiotic intake prenatally or perinatally, and gastric acidity inhibitors intake, which increase the risk of FA. Commensal diversity is a requirement for the maintenance of host homeostasis in the gut. To maintain ecological diversity and to avoid bacterial overgrowth, the immune system of the host must be regulated. It has been elucidated that a specific microbial consortium is responsive of tolerance to foods. On the other hand, dysbiosis in the gut is involved in inflammation, leading to pathogenesis and food allergy development. More studies are needed for a better understanding the causal relationships between microbiota, host, environment, and food allergy outcomes. The real role of other factors such as nutrition on the bacterial metabolome, and most importantly, on the mucosal immune responses, need to be re-evaluated. Recent successes in advanced molecular methodologies based on -omics technologies (i.e., proteomics, genomics, metabolomics) and systems biology approaches make them favorable strategies to analyze the relationship between gut microbiome and food allergies outcomes. In addition, future directions and new perspectives of omics-based systems biology approaches performed for the study of the mechanisms of food allergies and microbiome association will be described in this Special Issue.

• Microorganisms and food allergies, and their implication in immune responses
• Biomarker identification of FA progression
• Proteomics, Genomics and Metabolomics for the study of FA and microbiome relations
• Omics approaches/ Characterization of bacteria metabolites and their role in FA
• Antibiotic treatments and their potential implication in the development of food allergies
• Microbial transplant as a treatment to recover food allergies
• Probiotics and food dietary recommendations for food allergy patients

Dr. Ana González Abril
Dr. Mónica Carrera
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.