Special Issue "Environmental Sensitivity Illnesses: Mechanisms and Molecular Signatures"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 December 2019).
Interests: environmental sensitivity disorders; oxidative stress; genotype/phenotype relationships; neuroinflammation; immune activation; hyperhomocysteinemia-related disorders; hypovitaminosis D-related disorders; pathological role of transglutaminase 2 aberrant expression; neurological disorders
Special Issues and Collections in MDPI journals
This Special Issue aims to be a state-of-the-art review of environmental sensitivity illnesses (ESI), namely, multiple chemical sensitivity, fibromyalgia, chronic fatigue syndrome, and electrohypersensitivity, only to cite the most relevant ones. Despite these pathological conditions have recently gained a great interest, due to concerns about potential health risks raised by continuously increasing daily exposure to toxic xenobiotics, i.e., chemicals, drugs, artificial food components, heavy metals, and electro-magnetic fields, a nosologic classification of ESI is still lacking in a large number of countries worldwide.
The challenge set by this Special Issue is gathering high-quality research papers, as well as systematic reviews and meta-analyses, that focus on the following:
- Molecular mechanisms underlying shared and distinct features of different disorders arising from toxicant-induced loss of tolerance;
- Genetic and epigenetic alterations playing a role as risk factors, i.e., DNA (genomic, mitochondrial) sequence alterations, changes in either site-specific DNA methylation status or in circulating levels of microRNAs, and long non-coding RNAs;
- Distinctive alterations in the transcriptome and/or the proteome of peripheral blood cells, as well as in serum metabolome;
- Changes in gut microbioma and/or microbiota metabolites;
- Molecular tracers for neuroimaging.
I hope you will take the opportunity to share knowledge and new perspectives on these intringuing pathologies.
Prof. Dr. Daniela Caccamo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- multiple chemical sensitivity
- electromagnetic hypersensitivity
- toxicant-induced loss of tolerance
- chronic fatigue syndrome
- total allergy syndrome
- chronic pain disorder
- circulating biomarkers
- genetic susceptibility factors
- changes in DNA methylation status
- neuroimaging biomarkers