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Special Issue "New Advance on Cancer Stem Cells"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 31 August 2023 | Viewed by 3878
Special Issue Editor
Interests: cancer stem cell; artificial intelligence; RNAi screening; programed cell death; reactive oxygene species; mitochondrial membrane potential
Special Issue Information
A concept of cancer stem cells (CSCs) was introduced for the first time by Weissman IL in 2001 to consider rare cells with self-renewal potential that initiate tumorigenesis. It has been proven by many studies focusing on blood, breast, lung, liver, colon, stomach, and brain tumors, and melanoma. In recent years, the original concept has been reconstructed by considering plasticity of cell between differentiated and undifferentiated cells. The tumor microenvironment can stimulate differentiated tumor cells to acquire cancer stem cell characteristics. CSCs can originate not only from normal stem cells but also cancer cells. Although knowledge regarding the biology of CSCs is accumulating, it is not sufficient, with several gaps in topics such as the cell cycle, gene expression, cell senescence, niche, morphology, and sensitivity to therapeutics. Thus, more knowledge is required which can lead to the development of new diagnosis of CSCs and therapy targeting CSCs. This Special Issue aims to contribute to CSC research for cancer therapy. All research on CSC biology is welcome. This includes not only basic CSC biomarkers, cancer-associated fibroblast, CSC signaling, medicine including drugs, antibody, nucleic acid, and cell therapy and diagnosis, but also methods incorporating artificial intelligence technology. Through this issue, we hope to help scientists toward the development of CSC-based cancer therapy and diagnosis.
Dr. Tomoyasu Sugiyama
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- cancer stem cell
- cancer-associated fibroblast
- artificial intelligence
- cell therapy
- antibody therapy
- cell therapy
- gene expression