Proteomics of Body Fluids: Principles, Methods, and Applications

Dear Colleagues,

The routine work of most clinical laboratories involves, at least for the most part, the analysis of conventional biological matrices such as whole blood, serum, plasma, and urine. Therefore, the analysis of body fluids plays a critical role in the diagnosis and prognosis of disease. A change in the concentration or composition of a particular biochemical constituent in body fluids is used as an indicator of a physiological or pathological condition. Thus, a particular constituent in body fluids can be considered a marker for the detection of a disease. Driven by new biological discoveries and recent analytical breakthroughs, such as small volume aspiration and automated sample quality assessment, the analysis of body fluids such as saliva, semen, cerebrospinal fluid, peritoneal, pleural, pericardial, pancreatic, synovial, cystic, wound, drainage, and washout fluids, is becoming increasingly popular for the diagnosis and management of a kaleidoscope of human diseases. Therefore, this Special Issue of Proteomes on “Proteomics of Body Fluids: Principles, Methods, and Applications” welcomes submissions of original research or review articles that monitor a particular chemical species during disease progression, either an endogenous or exogenous compound that may also provide insight into the efficacy of a particular therapy. Health assessments and therapeutic screenings are also performed by analyzing body fluids. Many medical decisions depend on the results provided by the clinical laboratory in the analysis of body fluids. The clinical laboratory is thus tasked with providing reliable information for the detection, diagnosis, prognosis, prevention, and/or treatment of human diseases. It is therefore extremely important that the clinical laboratory be equipped with the latest and most appropriate analytical method for measuring chemical species in biological fluids.

Dr. Rui Vitorino
Guest Editor

Manuscript Submission Information

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