Sarcoma 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 21630
Special Issue Editor
Interests: sarcoma; chemotherapy; immunotherapy; biological reconstruction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Due to the rarity and heterogeneity of sarcoma, investigation into molecular targets and new treatments has been particularly challenging. Although intensive chemotherapy and the establishment of surgical procedures have improved the outcomes of patients with sarcomas, the curative rate of recurrent and metastatic sarcomas remains unsatisfactory. Recent basic science research has revealed some of the mechanisms of the progression and metastasis of malignancies, including proliferation, apoptosis, angiogenesis, tumor microenvironment, migration, invasion, and the regulation of antitumor immune systems. On the basis of these basic studies, new anticancer drugs have been developed, and the efficacies and safety of the new drugs have been assessed by clinical trials. This Special Issue aims to bring together the highest-quality original/review articles on basic and clinical research for bone and soft tissue tumors. We invite papers addressing molecular biology, microenvironment, and metastasis mechanisms, as well as those analyzing recent clinical research on new therapeutic approaches.
Dr. Shinji Miwa
Guest Editor
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Keywords
- sarcoma
- molecular target
- therapeutic target
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