Novel Biomarkers to Assess the Health Effects of Occupational and Environmental Exposure

Dear Colleagues,

Nowadays, the number of toxic substances on the market is increasing day by day. This fact has resulted in the whole population being chronically exposed to these chemicals, becoming one of the main social problems concerns within the scientific community due to their possible impact on public health. The problem increases when the exposure comes from an occupational environment. Working conditions, in some cases not following codes of good practices, involve additional exposure to that which is strictly necessary, leading to human health effects over the medium to long term.

The assessment of health effects due to chronic exposure to chemicals could be performed by identifying several specific biomarkers that may be predictive since they would be altered before the clinical manifestation (at sub-clinical or pre-clinical level). The use of novel biomarkers allows us to relate them to biochemical indicators of early toxic effects on target organs, as well as non-specific toxic effects, such as markers of oxidative stress. This relation also allows establishing a direct cause–effect relationship between chronic exposure and specific functional and organic alterations (molecular, biochemical, cellular, etc.) before the onset of disease symptoms.

According to that, all potential contributors are encouraged to submit original research and review papers on novel biomarkers for the assessment of the impact of chronic occupational or environmental exposure to any toxic substance on human health. These contributions are open to any area related to this topic.

Dr. David Lozano-Paniagua
Prof. Dr. Maria del Mar Requena Mullor
Prof. Dr. Raquel Alarcón
Guest Editors

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