Special Issue "Endocrine Disruptors and Public Health"
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601).
Deadline for manuscript submissions: closed (1 June 2016)
Dr. Huixiao Hong
National Center for Toxicological Research, U.S. Food and Drug Administration , 3900 NCTR Road, Building 5, Room 5C-109A, Jefferson, AR 72079, USA
Interests: pharmacogenomics; personalized medicine; toxicogenomics; bioinformatics; predictive toxicology
Endocrine disruptors (EDs) are exogenous compounds that act like hormones in the endocrine system and disrupt the physiologic function of endogenous hormones. Evidence that certain man-made chemicals have the ability to disrupt the endocrine systems, by mimicking endogenous hormones, sparked intense international scientific discussion and debate some fifteen years ago, culminating in language in legislation that reauthorized the Safe Drinking Water Act and authorized the 1996 Food Quality Protection Act, mandating that the Environmental Protection Agency (EPA) develop a screening program for endocrine disruptors. Since then, there have been a great amount of scientific efforts to understand the impact on the public health of EDs.
EDs could either mimic the endogenous hormones, causing over-responding or block the effects of a hormone from certain receptors, and therefore, resulting in adverse developmental, reproductive, neurological, and immune system effects. Many targets, such as estrogen and androgen receptors, related to the endocrine disrupting, have been studied. A variety of assays have been developed for measure endocrine related activity. The cumulative data and knowledge on the endocrine system, the mechanisms of endocrine disrupting, the impact on the public health of EDs and the regulatory responses to EDs will certain improve our understanding and predicting potential EDs and, thus, protect the public health.
This Special Issue aims to provide a forum to collect most recent progresses in all aspects of EDs and their impacts on the public health. Articles of the scientific findings on and the regulatory responses to EDS are solicited.
Dr. Huixiao Hong
Manuscript Submission Information
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