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Oral Health Outcomes from Childhood to Adulthood

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Global Health".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 503

Special Issue Editor


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Guest Editor
Dentistry Graduate Program, Federal University of Maranhão, São Luís 65080-805, Brazil
Interests: oral health; saliva; biomarkers; periodontitis; dental caries; healthcare; biofilms; immunology

Special Issue Information

Dear Colleagues,

We are pleased to announce a new Special Issue on "Oral Health Outcomes from Childhood to Adulthood". Oral health is a crucial element of overall quality of life and well-being. However, it frequently encounters obstacles in various stages of life. An understanding of the etiology of oral health problems from childhood to adulthood can inform the development of effective prevention and treatment strategies.

In childhood, common oral health problems include untreated dental caries, gingivitis, and orofacial clefts, which can have a significant impact on both physical health and quality of life. These conditions are exacerbated by poor oral hygiene practices, dietary habits, and limited access to dental care. Additionally, malocclusion and dental trauma are prevalent, often requiring orthodontic intervention as children grow.

As individuals transition into adolescence, the necessity for orthodontic intervention persists, accompanied by an elevated susceptibility to periodontal disease due to alterations in hormonal levels and behavioral patterns, including an increased consumption of sugary beverages and a decline in oral hygiene practices. It is also imperative to address tobacco use and other risk factors that can have a detrimental impact on oral health during this period.

In adulthood, the prevalence and complexity of oral health challenges tend to increase. Periodontal disease represents a significant concern, affecting not only oral health but also systemic health. A growing body of evidence suggests a link between periodontal disease and conditions such as diabetes and cardiovascular disease. Additionally, apical periodontitis and oral cancer are significant issues that require attention during this life stage. Dental caries remains a significant issue, often exacerbated by lifestyle factors, including dietary habits and access to dental care. Furthermore, adults may experience complications resulting from previous oral health concerns, necessitating oral rehabilitation interventions.

This Special Issue aims to highlight research on the oral health trajectory from childhood through adulthood, examining the factors that influence oral health outcomes across different age groups. We welcome contributions that explore epidemiological studies, policy implications, community-based interventions, clinical trials, treatment innovations, and systematic reviews that address the multifaceted nature of oral health throughout the lifespan.

We look forward to your contributions to this important area of research.

Yours sincerely,

Dr. Vandilson Rodrigues
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral health
  • public health
  • chronic disease
  • periodontitis
  • dental caries
  • dental care
  • saliva
  • dental occlusion
  • apical periodontitis

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Published Papers (1 paper)

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Research

13 pages, 3806 KiB  
Article
HLA Polymorphisms Linked to the Severity and Extent of Periodontitis in Patients with Type 1 Diabetes from a Brazilian Mixed Population
by Carlos Felipe Sousa Menezes, Lucas Meneses Lage, Luís Gustavo Souza Santos, Gilvan Cortês Nascimento, Marcelo Magalhães, Alexandre Facundo, Dayse Aparecida Silva, Luís Cristóvão Porto, Marília Brito Gomes, Manuel dos Santos Faria, Rossana Sousa Azulay and Vandilson Rodrigues
Int. J. Environ. Res. Public Health 2025, 22(4), 512; https://doi.org/10.3390/ijerph22040512 - 27 Mar 2025
Viewed by 266
Abstract
This study aimed to investigate the relationship between Class II human leukocyte antigen (HLA) alleles (DRB1, DQA1, and DQB1) and the severity and extent of periodontitis in patients with Type 1 diabetes (T1D). A cross-sectional study was conducted with 49 patients with T1D. [...] Read more.
This study aimed to investigate the relationship between Class II human leukocyte antigen (HLA) alleles (DRB1, DQA1, and DQB1) and the severity and extent of periodontitis in patients with Type 1 diabetes (T1D). A cross-sectional study was conducted with 49 patients with T1D. Demographic data and diabetes history were collected. A clinical examination was performed to assess periodontal variables. The patients were categorized by the periodontitis severity and the extent of periodontitis. Peripheral blood samples were analyzed to identify the percentage of autosomal ancestry (Native American, European, and African) and the HLA-DRB1*, HLA-DQA1*, and HLA-DQB1* alleles. The DRB1*03 and DRB1*15 haplogroups were significantly associated with an increased risk of generalized periodontitis (OR = 19.8, 95% CI = 1.14–346, p = 0.003; OR = 41.2, 95% CI = 1.85–917, p < 0.001) and severe periodontitis (OR = 7.7, 95% CI = 1.68–35.5, p = 0.003; OR = 21.2, 95% CI = 0.97–461, p = 0.005). No associations were observed between the HLA-DQA1 and HLA-DQB1 alleles and periodontitis. These findings suggest that patients with T1D from a highly mixed Brazilian population carrying the DRB1*03 and DRB1*15 haplogroups are at higher risk for developing more severe and generalized forms of periodontitis. Full article
(This article belongs to the Special Issue Oral Health Outcomes from Childhood to Adulthood)
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