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Prenatal Diagnosis, Fetal Treatment, and Feto-Placental Development

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Global Health".

Deadline for manuscript submissions: closed (2 November 2023) | Viewed by 1745

Special Issue Editor


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Guest Editor
Chair, Department of Obstetrics and Pathology of Pregnancy, Medical University of Lublin, 20-081 Lublin, Poland
Interests: pregnancy; fetoplacental development; fetal, placental, and the umbilical cord malformations; fetal monitoring; fetal therapies; prenatal diagnosis; prenatal ultrasonography; placental insufficiency; mesenchymal stem cells

Special Issue Information

Dear Colleagues,

This Special Issue will focus on important topics for obstetricians, perinatologists, neonatologists, pediatricians, and geneticists.

Obstetrics is a very dynamic field of medicine, with a growing interest in fetal and placental development. Expanding knowledge in terms of ultrasound, genetic, biochemical, and clinical insights is mandatory to provide reliable data to support clinical practice. Researchers and practitioners in this field have been looking at advances in pregnancy care including prevention, diagnosis, and treatment.

The early detection of fetal and placental abnormalities, their improper development, and  placenta-originated, fetal, and maternal complications (FGR, preeclampsia) is crucial for appropriate management. On the other hand, maternal illnesses (diabetes, neoplasms) may cause alterations in placental and fetal development and could contribute to suboptimal fetal outcomes.

These fetal abnormalities and maternal complications account for the leading causes of perinatal morbidity and mortality.

This Special Issue is open to submissions concerning the aforementioned medical specializations. I invite you to submit original research, systematic literature reviews, and meta-analyses.

Dr. Arkadiusz Robert Krzyżanowski
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • prenatal diagnosis
  • fetal imaging and biomarkers
  • fetal therapy
  • placenta and umbilical cord
  • placenta accreta spectrum
  • diabetes
  • preeclampsia
  • neoplasm
  • fetal growth restriction (FGR)
  • human genetics
  • mesenchymal stem cells

Published Papers (1 paper)

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Review

15 pages, 2505 KiB  
Review
A Review on Inflammasomes and Immune Checkpoints in Pre-Eclampsia Complicated with Tuberculosis and Human Immune Deficiency Virus
by Wendy N. Phoswa, Olive P. Khaliq and Simeon Eche
Int. J. Environ. Res. Public Health 2023, 20(17), 6627; https://doi.org/10.3390/ijerph20176627 - 22 Aug 2023
Viewed by 1469
Abstract
The current review evaluates how inflammasomes and immune checkpoints are regulated in pre-eclampsia (PE) associated with tuberculosis (TB) and Human Immune Deficiency Virus (HIV). Studies indicate that inflammasomes such as (NRLP3, NEK7, and AIM2) and immune checkpoints such as (CLT4, PD-1, TIM3, and [...] Read more.
The current review evaluates how inflammasomes and immune checkpoints are regulated in pre-eclampsia (PE) associated with tuberculosis (TB) and Human Immune Deficiency Virus (HIV). Studies indicate that inflammasomes such as (NRLP3, NEK7, and AIM2) and immune checkpoints such as (CLT4, PD-1, TIM3, and LAG-3) are dysregulated in TB- and HIV-infected individuals, and also in pre-eclamptic pregnancies, which explains why pregnant women who are either infected with TB or HIV have an increased risk of developing PE. Evidence suggests that inhibition of inflammasomes and immune checkpoints may assist in the development of novel anti-inflammatory drugs for the prevention and management of PE in patients with or without TB and HIV infection. Full article
(This article belongs to the Special Issue Prenatal Diagnosis, Fetal Treatment, and Feto-Placental Development)
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