Special Issues

Genes publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Plant Stress Biology and Crop Genetic Improvement: From Molecular Mechanisms to Breeding Applications
edited by
submission deadline 15 May 2027 | Viewed by 66 | Submission Open
Keywords: abiotic stress tolerance; biotic stress resistance; multi-omics integration; key gene identification; CRISPR/Cas9 gene editing; epigenetic regulation; improvement of stress, yield, and quality; root biology and resource efficiency; phytohormone signaling; germplasm evaluation and utilization; secondary metabolites in defense; genomic selection and prediction; phenomics and high-throughput screening; AI and machine learning; phenotypic plasticity
(This special issue belongs to the Section Plant Genetics and Genomics)
Animal Mating Strategies: Insight from Molecular Genetics
edited by Robert Rutkowski
submission deadline 15 May 2027 | Viewed by 52 | Submission Open
Keywords: animal mating strategies; sexual selection; reproductive success; parentage analysis; kinship and relatedness; molecular ecology; evolutionary ecology; extra-pair patternity; conservation genetics
(This special issue belongs to the Section Animal Genetics and Genomics)
Genomic Advances in Inherited Metabolic Diseases: From Variant Interpretation to Precision Medicine
edited by
submission deadline 15 May 2027 | Viewed by 45 | Submission Open
Keywords: inherited metabolic diseases; genomic diagnosis; variant interpretation; multi-omics; precision medicine
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Genetics, Genomics and Breeding of Rapeseed (Brassica napus L.)
edited by and Yourong Chai
submission deadline 15 May 2027 | Viewed by 30 | Submission Open
Keywords: rapeseed (Brassica napus); genetics; plant breeding; genomics; genome editing; molecular breeding; GWAS and QTL mapping; genomic selection; abiotic and biotic stress resistance; oil quality and yield
(This special issue belongs to the Section Plant Genetics and Genomics)
Genomic and Molecular Determinants of HPV-Related Reproductive Health submission deadline 20 May 2027 | 1 articles | Viewed by 1210 | Submission Open
Keywords: human papillomavirus (HPV); viral genomics; epigenomics; proteomics; vaginal microbiome; intestinal microbiome; metabolic pathways; oxidative stress; infertility genetics; reproductive health; personalized medicine; precision medicine; AI-driven diagnostics
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Next-Generation Proteogenomics
edited by Indranil Paul
submission deadline 20 May 2027 | Viewed by 321 | Submission Open
Keywords: proteogenomics; mass spectrometry; machine learning; AI and LLMs; data integration; single-cell proteomics; spatial proteomics; genotype-phenotype mapping; precision medicine
(This special issue belongs to the Section Bioinformatics)
Gene Expression Perturbations and In Vitro Systems in Applied Toxicology: From Measurement to Biological Interpretation
edited by Bhaja Krushna Padhi
submission deadline 20 May 2027 | Viewed by 151 | Submission Open
Keywords: gene expression; alternative splicing; mRNA biomarkers; targeted transcriptomics; molecular toxicology; gene orthology; in vitro toxicology; chemical toxicity assessment; regulatory toxicology; new approach methodologies (NAMs)
(This special issue belongs to the Section Toxicogenomics)
Genetic Analysis of Challenging Forensic Samples: Degradation, Environmental Factors, and Molecular Temporal Inference
edited by
submission deadline 20 May 2027 | Viewed by 87 | Submission Open
Keywords: forensic DNA analysis; forensic genetics; DNA profiling; probabilistic genotyping; forensic genetic genealogy; DNA extraction; DNA sequencing
(This special issue belongs to the Section Molecular Genetics and Genomics)
Genetics of Embryonic Organogenesis: From Cell Differentiation to Disease submission deadline 20 May 2027 | Viewed by 37 | Submission Open
Keywords: embryonic organogenesis; cell differentiation; developmental signaling pathways; lineage specification; nephrogenesis; congenital anomalies of the kidney and urinary tract (CAKUT); congenital malformations; single-cell and spatial transcriptomics; organoids; animal models of development; immunohistochemistry and immunofluorescence; developmental pathways in disease and cancer
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Exploring the Genetics and Genomics of Neuromuscular Disorders
edited by Liubov V. Gushchina and Michael J. Keogh
submission deadline 20 May 2027 | Viewed by 34 | Submission Open
Keywords: neuromuscular diseases; molecular mechanisms; genetic diagnostics; biomarkers; advanced therapies
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
From Short Reads to Long Reads: Sequencing Technologies in Genomics and Gene Discovery
edited by
submission deadline 20 May 2027 | Viewed by 17 | Submission Open
Keywords: bioinformatics; long reads; genomics; transcriptomics; algorithms
(This special issue belongs to the Section Technologies and Resources for Genetics)
Genetics, Diversity and Evolution of Molluscs
edited by Marianna Soroka
submission deadline 25 May 2027 | 1 articles | Viewed by 1766 | Submission Open
Keywords: molluscs; genetics; DNA; genomes; Barcode DNA; DNA sequencing; DUI; diversity; evolution; native; alien and invasive species; hybridisation zones
(This special issue belongs to the Section Animal Genetics and Genomics)
Genetic and Epigenetic Architecture of Complex Cardiovascular Traits
edited by and Mariana Bezamat Chappel
submission deadline 25 May 2027 | 1 articles | Viewed by 854 | Submission Open
Keywords: cardiovascular disease; genetics/genomics; epigenetics/epigenomics; omics; precision medicine; genotype–phenotype correlations; gene–gene interactions
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Molecular Mechanisms and Genetics of Sex Determination in Insects
edited by
submission deadline 25 May 2027 | Viewed by 55 | Submission Open
Keywords: sex determination; gene function; regulatory elements; epigenetic modifications; sex chromosomes; non-coding RNAs; pest management; genome editing
(This special issue belongs to the Section Animal Genetics and Genomics)
Ancient DNA in the Genomic Era: Innovation and Discovery
edited by Sally Wasef, and
submission deadline 25 May 2027 | Viewed by 6 | Submission Open
Keywords: ancient DNA; next generation sequencing; bioinformatics; forensic human identification; degraded DNA; population genomics; molecular genetics; contamination assessment; human evolution
(This special issue belongs to the Section Population and Evolutionary Genetics and Genomics)
Epigenetic Regulation of Germline Cells: From Meiosis to Epigenetic Inheritance
edited by Elena De la Casa-Esperon
submission deadline 5 Jun 2027 | 1 articles | Viewed by 1123 | Submission Open
Keywords: epigenetic regulation; germline cells; meiosis; meiotic recombination; chromosome segregation; environmental effects on germline; 3D genome organization; transgenerational epigenetic inheritance
(This special issue belongs to the Section Epigenomics)
Genetics and Genomics of Climate Resilience in Livestock submission deadline 10 Jun 2027 | Viewed by 45 | Submission Open
Keywords: livestock genetics; genomics; climate resilience; heat tolerance; genomic selection; animal breeding; environmental adaptation; genotype-by-environment interaction
(This special issue belongs to the Section Animal Genetics and Genomics)
Clinical Genomics and Precision Medicine: From Genetic Testing to Clinical Decision-Making
edited by
submission deadline 10 Jun 2027 | Viewed by 29 | Submission Open
Keywords: clinical genomics; precision medicine; genetic testing; variant interpretation; genotype–phenotype correlation; next-generation sequencing; genomic medicine; clinical decision-making; genetic disorders; genetic counselling
(This special issue belongs to the Section Genetic Diagnosis)
Genetic Risk and Mutation‑Specific Pathways in Rare Disorders
edited by
submission deadline 10 Jun 2027 | Viewed by 18 | Submission Open
Keywords: genetics; rare diseases; gene therapy; genotype-phenotype correlation; genetic variants
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
AI-Powered Transcriptomic Profiling: Biomarkers and Precision Immunotherapy
edited by Nicole Bussola
submission deadline 10 Jun 2027 | Viewed by 14 | Submission Open
Keywords: deep learning; transcriptomics; biomarker discovery; computational immunology; precision immunotherapy
(This special issue belongs to the Section Bioinformatics)
Advances in Omics of Arthropod Vectors
edited by , Yoonseong Park, Kristopher Silver and Dana Mitzel
submission deadline 15 Jun 2027 | Viewed by 86 | Submission Open
Keywords: arthropod vectors; pest control; pathogen interactions; vector biology; genes; genomics; epigenomics; genetics; animal health; crop protection
(This special issue belongs to the Section Animal Genetics and Genomics)
Genomic and Genetic Determinants of Liver Health and Disease
edited by Ralf Weiskirchen
submission deadline 15 Jun 2027 | Viewed by 57 | Submission Open
Keywords: liver genetics; human genomics; metabolic liver disease; MASLD/MASH genetics; hepatocellular carcinoma genetics; genomic biomarkers; precision hepatology; GWAS and sequencing; functional genomics; liver disease susceptibility
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Genetic Architecture of Wheat Domestication- and Improvement-Related Traits
edited by Panfeng Guan
submission deadline 20 Jun 2027 | 1 articles | Viewed by 1018 | Submission Open
Keywords: wheat; origin and evolution; domestication syndrome; genetic diversity; genetic improvement; gene mapping and cloning; molecular mechanism and function; molecular breeding; pan-omics; new approaches
(This special issue belongs to the Section Plant Genetics and Genomics)
Integrative Applications of Flow Cytometry, Fluorescence Microscopy, and Molecular Markers in Plant and Fungal Genetics submission deadline 25 Jun 2027 | Viewed by 68 | Submission Open
Keywords: cell cycle; endoreduplication; genetic diversity; genome size; microscopy; molecular markers; mycology; ploidy; polysomaty; somaclonal variation
(This special issue belongs to the Section Molecular Genetics and Genomics)
Genetics and Breeding of Aquaculture
edited by Kaiqiang Zhang
submission deadline 25 Jun 2027 | Viewed by 15 | Submission Open
Keywords: fish genetic breeding; aquaculture germplasm; functional gene; multi-omics; genomic selection; cross breeding; mitochondrial genetics
(This special issue belongs to the Section Animal Genetics and Genomics)
Genetic Diagnosis and Molecular Therapeutics in Cardiomyopathy
edited by Dorota Ciołczyk-Wierzbicka
submission deadline 10 Jul 2027 | Viewed by 59 | Submission Open
Keywords: cardiomyopathy; genetic diagnosis; cardiovascular genomics; precision medicine; molecular therapeutics; gene therapy; RNA therapeutics; liquid biopsy; artificial intelligence; multi-omics
(This special issue belongs to the Section Genetic Diagnosis)
Dynamic Chromatin Architecture: Shared Mechanisms Governing Accessibility Across DNA-Templated Processes
edited by Yesenia Rodriguez and Surbhi Sood
submission deadline 10 Jul 2027 | Viewed by 20 | Submission Open
Keywords: chromatin architecture; transcription; DNA repair; genomics; nucleosome dynamics; histone variants; histone post-translational modifications; DNA modifications; ATP-dependent chromatin remodeling
(This special issue belongs to the Section Molecular Genetics and Genomics)
Genetic Research of Neurodevelopmental Disorders
edited by , Laura Bernardini and
submission deadline 10 Jul 2027 | Viewed by 19 | Submission Open
Keywords: CNVs; epigenetics; functional validation; multi-omics; neurodevelopmental disorders; SNVs; targeted therapies
(This special issue belongs to the Section Neurogenomics)
Mitochondrial DNA Variation in Health and Disease
edited by Ludmiła A. Grzybowska-Szatkowska, Katarzyna Bartosik and Marzanna Ciesielka
submission deadline 15 Jul 2027 | Viewed by 369 | Submission Open
Keywords: mitochondrial DNA; single-nucleotide polymorphism; carcinogenesis; apoptosis; mitochondrial haplogroups
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Genetic and Genomic Studies of Lysosomal Storage Diseases submission deadline 10 Aug 2027 | Viewed by 43 | Submission Open
Keywords: lysosomal storage diseases; molecular genetics; lysosomal biology; genetic diagnosis; RNA therapeutics; genome editing; precision medicine
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Environmental DNA (eDNA) in Ecology
edited by Jeffrey A. Miller
submission deadline 15 Aug 2027 | Submission Open
Keywords: environmental DNA; eDNA; metabarcoding; biodiversity monitoring; molecular ecology; species detection; bioinformatics; PCR and sequencing bias; conservation genetics; fisheries, terrestrial, and aquatic ecosystem management/montoring
(This special issue belongs to the Section Genes & Environments)
Genetic Dissection of Nutrient Sensing and Response Mechanisms from Model Plants to Crops
edited by Zhi-Liang Zheng
submission deadline 20 Aug 2027 | Viewed by 21 | Submission Open
Keywords: nutrient sensing; gene expression; cellular signaling; nutrient use efficiency; biotechnology
(This special issue belongs to the Section Plant Genetics and Genomics)
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