The Genetic Basis of Mental Disorders
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Human Genomics and Genetic Diseases".
Deadline for manuscript submissions: closed (15 February 2024) | Viewed by 4693
Special Issue Editors
Interests: genetics; polygenic risk scores; psychosis; stress-related disorders
Special Issues, Collections and Topics in MDPI journals
Interests: medical statistics; psychiatric epidemiology; epidemiological designs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, considerable efforts have been made to better understand the genetic basis of mental disorders, such as schizophrenia, bipolar disorder, depression, eating disorders and obsessive–compulsive disorders. Several large-scale and collaborative projects applying modern genomic methods are starting to reveal the genetic architecture of these disorders and identify long-sought risk genes. However, it is not completely understood whether environmental factors increase vulnerability independent of genetic risk, interact with it, or are a manifestation of a predisposition to mental disorders. In this context, a new challenge has arisen regarding the search for biomarkers that, together with the results of other investigations, can accelerate proper diagnosis and treatment.
The purpose of this Special Issue is to summarize what we currently know about the genomics of mental disorders and the contribution of environmental factors. The Special Issue will focus on experimental papers and review articles that discuss the genetic basis of mental disorders and the contribution of environmental factors to the biological vulnerability that shapes both the onset and the course of mental disorders. This Special Issue also seeks papers that discuss molecular biomarkers, and their use in prognostic models or in the validation of mental disorders.
Dr. Sarah Tosato
Dr. Chiara Bonetto
Guest Editors
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