Multi-Omics in Psychiatric Disorders
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Neurogenomics".
Deadline for manuscript submissions: 15 October 2025 | Viewed by 81
Special Issue Editors
Interests: multi-omics; psychiatric disorders; functional genomics; integrative studies; precision medicine
Special Issue Information
Dear Colleagues,
Psychiatric disorders are characterized by distress in the behavior, cognition, and emotions of an individual. According to the Global Burden of Disease, psychiatric disorders are one of the groups of disorders that contribute the most to global morbidity. In 2019, it was estimated that one in eight people were diagnosed with a psychiatric condition, and after the COVID-19 pandemic, we observed an increase in those numbers (e.g., an increase of 26% in a year in anxiety disorders). Studies have shown that the complexity of psychiatric disorders involves the interplay of biological and environmental factors in their development.
Several studies have shown the genetic heritability of psychiatric disorders. Hundreds of loci have already been identified as associated with psychiatric disorders using tools such as genome-wide association studies. Furthermore, current efforts are being made to characterize their function and develop novel therapies. Even with the substantial progress in the understanding of the genomic architecture of psychiatric disorders, it still explains a small proportion of the phenotypic variance. In this context, some studies proposed that the molecular underpinnings of psychiatric disorders could be understood by investigating additional layers of biological information, including DNA, RNA, proteins, and regulatory mechanisms, known as multi-omics.
There are still limited studies involved in investigating multi-omics in psychiatric disorders, which would provide additional information to uncover novel therapeutic approaches.
In this Special Issue, we welcome review articles and original research on developing and applying multi-omics techniques to disentangle molecular mechanisms in psychiatric disorders. This Special Issue will also accept studies involving several omics, such as genomics, epigenomics, transcriptomics, exposomics, and proteomics. Our study section will not be restricted to the omics cited here but to emerging omic applications and integration with in vitro or in vivo models. We aim for the edition to emphasize the importance of understanding the molecular mechanisms involved in the etiology and severity of psychiatric disorders as an integrative mechanism to potentially develop novel biomarkers and therapeutic approaches. We look forward to your contribution.
Dr. José Jaime Martínez-Magaña
Dr. Sheila T. Nagamatsu
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- methylomics
- transcriptomics
- epigenomics
- genomics
- proteomics
- metabolomics
- multi-omics
- psychiatric disorders
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
