Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.7
5.0
Journals
Gels
Special Issues
Organogels for Biomedical Applications
share announcement

Organogels for Biomedical Applications

A special issue of Gels (ISSN 2310-2861).

Deadline for manuscript submissions: closed (31 July 2017) | Viewed by 40850

Special Issue Editor

Prof. Dr. Xian Jun Loh

grade E-Mail Website
Guest Editor
Institute of Materials Research and Engineering (IMRE), A*STAR, 3 Research Link, Singapore 117602, Singapore
Interests: water soluble polyhydroxyalkanoates; biodegradable thermogelling polymers; supramolecular host–guest polymeric materials for biomedical applications
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

An organogel belongs to a class of gel composed of a liquid organic phase within a three-dimensional, cross-linked network. Organogel networks can form by a classic gel network formation via polymerization. However, organogels that are “low molecular weight gelators” can also be designed to form gels via self-assembly. Secondary forces, such as van der Waals or hydrogen bonding, cause monomers to cluster into a non-covalently bonded network that retains organic solvent, and, as the network grows, it exhibits gel-like physical properties.

Organogels are thermodynamically stable in nature and can be used as matrices for the delivery of bioactive agents. In this Special Issue, we are looking for papers that look at various aspects of organogels for biomedical applications.

  1. Tissue engineering
  2. Drug release including mechanism of release
  3. Fabrication and novel synthesis of organogels for biomedical applications
  4. Pharmacologically relevant organogels
  5. Mechanism of formation of organogels

Dr. Xian Jun Loh
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gels is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


Keywords

  • Drug delivery
  • Tissue engineering
  • injectable
  • rheological

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (4 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review

2351 KiB  
Article
Ultrasound- and Temperature-Induced Gelation of Gluconosemicarbazide Gelator in DMSO and Water Mixtures
by Mothukunta Himabindu and Aruna Palanisamy
Gels 2017, 3(2), 12; https://doi.org/10.3390/gels3020012 - 18 Apr 2017
Cited by 15 | Viewed by 6245
Abstract
We have developed amphiphilic supramolecular gelators carrying glucose moiety that could gel a mixture of dimethyl sulfoxide (DMSO) and water upon heating as well as ultrasound treatment. When the suspension of gluconosemicarbazide was subjected to ultrasound treatment, gelation took place at much lower [...] Read more.
We have developed amphiphilic supramolecular gelators carrying glucose moiety that could gel a mixture of dimethyl sulfoxide (DMSO) and water upon heating as well as ultrasound treatment. When the suspension of gluconosemicarbazide was subjected to ultrasound treatment, gelation took place at much lower concentrations compared to thermal treatment, and the gels transformed into a solution state at higher temperatures compared to temperature-induced gels. The morphology was found to be influenced by the nature of the stimulus and presence of salts such as KCl, NaCl, CaCl2 and surfactant (sodium dodecyl sulphate) at a concentration of 0.05 M. The gel exhibited impressive tolerance to these additives, revealing the stability and strength of the gels. Fourier transform infrared spectroscopy (FTIR) revealed the presence of the intermolecular hydrogen bonding interactions while differential scanning calorimetry (DSC) and rheological studies supported better mechanical strength of ultrasound-induced (UI) gels over thermally-induced (TI) gels. Full article
(This article belongs to the Special Issue Organogels for Biomedical Applications)
►▼ Show Figures

Graphical abstract

Review

Jump to: Research

16628 KiB  
Review
Poly(N-isopropylacrylamide) and Copolymers: A Review on Recent Progresses in Biomedical Applications
by Sonia Lanzalaco and Elaine Armelin
Gels 2017, 3(4), 36; https://doi.org/10.3390/gels3040036 - 4 Oct 2017
Cited by 286 | Viewed by 19238
Abstract
The innate ability of poly(N-isopropylacrylamide) (PNIPAAm) thermo-responsive hydrogel to copolymerize and to graft synthetic polymers and biomolecules, in conjunction with the highly controlled methods of radical polymerization which are now available, have expedited the widespread number of papers published in the [...] Read more.
The innate ability of poly(N-isopropylacrylamide) (PNIPAAm) thermo-responsive hydrogel to copolymerize and to graft synthetic polymers and biomolecules, in conjunction with the highly controlled methods of radical polymerization which are now available, have expedited the widespread number of papers published in the last decade—especially in the biomedical field. Therefore, PNIPAAm-based hydrogels are extensively investigated for applications on the controlled delivery of active molecules, in self-healing materials, tissue engineering, regenerative medicine, or in the smart encapsulation of cells. The most promising polymers for biodegradability enhancement of PNIPAAm hydrogels are probably poly(ethylene glycol) (PEG) and/or poly(ε-caprolactone) (PCL), whereas the biocompatibility is mostly achieved with biopolymers. Ultimately, advances in three-dimensional bioprinting technology would contribute to the design of new devices and medical tools with thermal stimuli response needs, fabricated with PNIPAAm hydrogels. Full article
(This article belongs to the Special Issue Organogels for Biomedical Applications)
►▼ Show Figures

Graphical abstract

5249 KiB  
Review
Colloidal Dispersions of Gelled Lipid Nanoparticles (GLN): Concept and Potential Applications
by Mariana Carrancá Palomo, Victoria Martín Prieto and Plamen Kirilov
Gels 2017, 3(3), 33; https://doi.org/10.3390/gels3030033 - 10 Sep 2017
Cited by 19 | Viewed by 6745
Abstract
The interest in using colloidal dispersions of gelled lipid nanoparticles (GLN) for different fields of application has increased in recent years, notably in cosmetic, dermatology, and/or pharmaceutics due to their capacity to immobilize compounds with poor water solubility. The pharmaceutical field desires to [...] Read more.
The interest in using colloidal dispersions of gelled lipid nanoparticles (GLN) for different fields of application has increased in recent years, notably in cosmetic, dermatology, and/or pharmaceutics due to their capacity to immobilize compounds with poor water solubility. The pharmaceutical field desires to achieve lipophilic drug formulations which are able to conserve their stability, although it is well-known that emulsions and solid lipid nanoparticles (SLN) present a lack of stability over time, leading to system destabilization. Furthermore, stable colloidal dispersions of gelled oil particles do not affect the properties of the molecule to be delivered, and they result as an alternative for the previously appointed systems. This review is an attempt to present the reader with an overview of colloidal dispersions of GLN, their concept, formulation methods, as well as the techniques used for their characterization. Moreover, various application fields of organogel dispersions have been illustrated to demonstrate the potential application range of these recent materials. Full article
(This article belongs to the Special Issue Organogels for Biomedical Applications)
►▼ Show Figures

Graphical abstract

1192 KiB  
Review
Low-Molecular-Weight Gelators as Base Materials for Ointments
by Yutaka Ohsedo
Gels 2016, 2(2), 13; https://doi.org/10.3390/gels2020013 - 1 Apr 2016
Cited by 30 | Viewed by 7282
Abstract
Ointments have been widely used as an efficient means of transdermal drug application for centuries. In order to create ointments suitable for various new medicinal drugs, the creation of ointment base materials, such as gels, has attracted much research attention in this decade. [...] Read more.
Ointments have been widely used as an efficient means of transdermal drug application for centuries. In order to create ointments suitable for various new medicinal drugs, the creation of ointment base materials, such as gels, has attracted much research attention in this decade. On the other hand, the chemical tuning of low-molecular-weight gelators (LMWGs) has been increasingly studied for two decades because LMWGs can be tailored for different purposes by molecular design and modification. In this review, several series of studies related to the creation of ointment base materials with enhanced properties using existing and newly-created LMWGs are summarized. Full article
(This article belongs to the Special Issue Organogels for Biomedical Applications)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-4
Back to TopTop