Foodomics Approaches—Technologies and Their Applications

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Foodomics".

Deadline for manuscript submissions: closed (25 April 2025) | Viewed by 1425

Special Issue Editors


E-Mail Website
Guest Editor
Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece
Interests: foodomics; NMR spectroscopy; metabolomics; chemometrics; food authenticity; wine analysis; grape marc distillates; food traceability; antioxidant activity
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Institute of Chemical Biology, National Hellenic Research Foundation, 11635 Athens, Greece
Interests: NMR-based metabolomics; biomarker discovery, nutrimetabolomics, high throughput fingerprinting of natural products; in silico methods; bioNMR
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue of Foods focuses on “Foodomics ApproachesTechnologies and Their Applications”. Foodomics is a comprehensive, high-throughput tool facilitating food science to improve human nutrition. This new approach to food and nutrition studies the food domain as a whole, alongside the nutrition domain, achieving the main objective of optimizing human health and well-being. Thus, it provides valuable insights into food safety, quality control, and authenticity, enabling better regulatory practices and ensuring consumer trust. In recent years, the applications of foodomics span the food system, from production, processing, distribution, and storage (food authenticity, traceability, and safety) to consumption, including dietary guidelines and the emerging field of precision nutrition. Specifically, NMR-based and MS-based metabolomic approaches have been applied to study food at the molecular level and advance nutritional food research by controlling food quality and safety, identifying health-promoting food constituents and investigating the impact of dietary patterns in relation to human health.

Therefore, this Special Issue is open to receiving research results and/or quality reviews on the new challenges and technological and nutritional approaches related to omics technologies, especially foodomics.

Dr. Charalambos Fotakis
Dr. Maria Zervou
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • foodomics
  • omics technologies
  • metabolomics
  • genomics
  • proteomics
  • food analysis
  • bioactive compounds
  • nutraceuticals
  • human health
  • food quality

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

18 pages, 5494 KiB  
Article
Transcriptomic Profiling Uncovers Molecular Basis for Sugar and Acid Metabolism in Two Pomegranate (Punica granatum) Varieties
by Ding Ke, Yilong Zhang, Yingfen Teng and Xueqing Zhao
Foods 2025, 14(10), 1755; https://doi.org/10.3390/foods14101755 - 15 May 2025
Viewed by 316
Abstract
Soluble sugars and organic acids constitute the primary flavor determinants in fruits and elucidating their metabolic mechanisms provides crucial theoretical foundations for fruit breeding practices and food industry development. Through integrated physiological and transcriptomic analysis of pomegranate varieties ‘Sharp Velvet’ with high acid [...] Read more.
Soluble sugars and organic acids constitute the primary flavor determinants in fruits and elucidating their metabolic mechanisms provides crucial theoretical foundations for fruit breeding practices and food industry development. Through integrated physiological and transcriptomic analysis of pomegranate varieties ‘Sharp Velvet’ with high acid content and ‘Azadi’ with low acid content, this study demonstrated that the differences in flavor between the two varieties were mainly caused by differences in citric acid content rather than in soluble sugar content. Transcriptome profiling identified 11 candidate genes involved in sugar and acid metabolism, including three genes associated with soluble sugar metabolism (FBA1, SS, and SWEET16) and eight genes linked to organic acid metabolism (ADH1, GABP1, GABP2, GABP3, GABP4, ICL, ME1, and PDC4). These data indicated that differences in citric acid content between the two varieties mainly stemmed from differences in the regulation of the citric acid degradation pathway, which relies mainly on the γ-aminobutyric acid (GABA) branch rather than the isocitric acid lyase (ICL) pathway. Citric acid accumulation in pomegranate fruit was driven by metabolic fluxes rather than vesicular storage capacity. Weighted gene co-expression network analysis (WGCNA) uncovered a significant citric acid content associated module (r = −0.72) and predicted six core transcriptional regulators (bHLH42, ERF4, ERF062, WRKY6, WRKY23, and WRKY28) within this network. Notably, bHLH42, ERF4, and WRKY28 showed significant positive correlations with citric acid content, whereas ERF062, WRKY6, and WRKY23 demonstrated significant negative correlations. Our findings provide comprehensive insights into the genetic architecture governing soluble sugars and organic acids homeostasis in pomegranate, offering both a novel mechanistic understanding of fruit acidity regulation and valuable molecular targets for precision breeding of fruit quality traits. Full article
(This article belongs to the Special Issue Foodomics Approaches—Technologies and Their Applications)
Show Figures

Figure 1

Back to TopTop