Novel Detection Approaches of Biological and Non-Biological Risk Factors in Foods—2nd Edition

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Analytical Methods".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 340

Special Issue Editors


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Guest Editor
School of Food Science and Engineering, Yangzhou university, Yangzhou 225127, China
Interests: agricultural pathogens; mycotoxins; biocontrol
Special Issues, Collections and Topics in MDPI journals
Department of Food Science & Engineering, Yangzhou University, Yangzhou, China
Interests: food safety; rapid detection technology; animal-derived food; veterinary residues; foodborne pathogens
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Food contaminants include biological and non-biological risk factors, such as foodborne pathogens, mycotoxins, heavy metals, pesticides, veterinary drugs, and illegal additives, which pose serious threats to public health and food safety. Developing quick and sensitive detection methods to determine food contaminants is necessary. Instrumental techniques, such as liquid chromatography (LC), gas chromatography (GC), LC–tandem mass spectrometry (MS/MS), and GC–MS/MS, have become well established in food analysis. Additionally, instrument analysis usually requires a combination of sample preparation methods, including solid-phase extraction, QuEChERS, and accelerated solvent extraction. Meanwhile, polymerase chain reaction (PCR), enzyme-linked immunosorbent assay (ELISA), and biosensors supplement the instruments, providing new methods for rapidly detecting food contaminants. Establishing a novel, quick, and sensitive detection method provides new technical support and theoretical basis for detecting food contaminants, which is significant in ensuring food safety. Therefore, this Special Issue aims to publish the latest research on novel detection approaches for biological and non-biological risk factors in foods, which involve instrument methods, PCR, ELISA, and biosensors to detect food contaminants. Additionally, reviews of different detection methods for food contaminants are also welcome.

Dr. Xiangfeng Zheng
Dr. Bo Wang
Guest Editors

Manuscript Submission Information

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Keywords

  • pesticides
  • veterinary drugs
  • mycotoxins
  • foodborne pathogens
  • illegal additives
  • instrumental analysis methods
  • biosensor
  • ELISA
  • PCR

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Published Papers (1 paper)

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Research

22 pages, 3291 KiB  
Article
Matrix Interference Removal Using Fe3O4@SiO2-PSA-Based Magnetic Dispersive Solid-Phase Extraction for UPLC-MS/MS Analysis of Diazepam in Aquatic Products
by Mengqiong Yang, Guangming Mei, Daoxiang Huang, Xiaojun Zhang, Pengfei He and Si Chen
Foods 2025, 14(14), 2421; https://doi.org/10.3390/foods14142421 - 9 Jul 2025
Viewed by 242
Abstract
A sensitive method was developed for detecting diazepam residues in aquatic products using magnetic dispersive solid-phase extraction (MDSPE) coupled with ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS). Samples extracted with 1% ammonia–acetonitrile were purified using synthesized Fe3O4@SiO2-PSA nanoparticles [...] Read more.
A sensitive method was developed for detecting diazepam residues in aquatic products using magnetic dispersive solid-phase extraction (MDSPE) coupled with ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS). Samples extracted with 1% ammonia–acetonitrile were purified using synthesized Fe3O4@SiO2-PSA nanoparticles via MDSPE before UPLC-MS/MS analysis. Separation was performed on a C18 column with gradient elution using 0.1% formic acid–2 mM ammonium acetate/methanol. Detection employed positive electrospray ionization (ESI+) in multiple reaction monitoring (MRM) mode. Characterization confirmed Fe3O4@SiO2-PSA’s mesoporous structure with excellent adsorption capacity and magnetic properties. The method showed good linearity (0.1–10 μg/L, r > 0.99) with an LOD and LOQ of 0.20 μg/kg and 0.50 μg/kg, respectively. Recoveries at 0.5–15.0 µg/kg spiking levels were 74.9–109% (RSDs 1.24–11.6%). This approach provides rapid, accurate, and high-precision analysis of diazepam in aquatic products, meeting regulatory requirements. Full article
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