Next-Generation Chemometric and Spectroscopic Strategies for Food Safety and Authenticity: Toward Faster and More Reliable Detection

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Analytical Methods".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 542

Special Issue Editor


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Guest Editor
Chemometrics and Sensorics for Analytical Solutions (CHEMOSENS), Department of Analytical and Organic Chemistry, Rovira i Virgili University, Marcel·lí Domingo s/n, 43007 Tarragona, Spain
Interests: multivariate data analysis; spectroscopy; qualitative performance parameters; food fraud; data fusion
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Special Issue Information

Dear Colleagues,

The increasing complexity of global food supply chains, combined with recurring cases of food fraud and contamination, has intensified the need for rapid, robust, and interpretable analytical tools. Spectroscopic techniques, especially when integrated with chemometrics, machine learning, or deep learning, offer non-destructive, sustainable, and high-throughput solutions for food safety and authenticity assessment.

This Special Issue invites original research and reviews focused on developing and applying innovative spectroscopic and chemometric methodologies for real-time or near-real-time food analysis. Emphasis will be placed on defining, estimating, and validating performance parameters—critical aspects that remain underexplored and that are currently lacking in regulatory consensus. Submissions addressing these challenges through new protocols, benchmarking approaches, or validation frameworks will be highly valued.

We are particularly interested in contributions that considering the following:

  • Present novel chemometric workflows for multivariate calibration, classification, or detection;
  • Explore spectral preprocessing and data fusion techniques to enhance model robustness;
  • Propose standardized strategies for reporting accuracy, precision, sensitivity, specificity, and model transferability;
  • Demonstrate the real-world applicability of these methods through case studies on food fraud, adulteration, or contamination.

By addressing both methodological innovation and performance validation, this Special Issue will advance the field toward reliable, transparent, and regulatory-ready solutions for ensuring food integrity.

Join us in shaping next-generation tools for food safety, which will be faster, smarter, and scientifically rigorous.

Prof. Dr. Itziar Ruisánchez Capelastegui
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • food safety
  • food authenticity
  • chemometrics
  • spectroscopy
  • multivariate analysis
  • machine learning
  • rapid detection
  • non-destructive analysis
  • model validation
  • food fraud

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Published Papers (1 paper)

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Research

25 pages, 5029 KB  
Article
An Exploratory Study on the Influence of Frying on Chemical Constituent Transformation and Antioxidant Activity in Ziziphi Spinosae Semen: A Multimodal Analytical Strategy Based on UPLC–Q–TOF–MS and GC–IMS
by Xinyi Ouyang, Xiaonuo Shi, Chang Zhou, Mengyuan Li, Rujia Huang, Huiping Liu, Dan Huang and Guomin Zhang
Foods 2025, 14(23), 4145; https://doi.org/10.3390/foods14234145 - 3 Dec 2025
Viewed by 315
Abstract
Ziziphi Spinosae semen (ZSS) is renowned for its rich nutritional composition and is traditionally consumed in China, Japan, and Korea, where it is widely incorporated into both medicinal diets and daily cuisine. To address the lack of systematic research comparing raw and fried [...] Read more.
Ziziphi Spinosae semen (ZSS) is renowned for its rich nutritional composition and is traditionally consumed in China, Japan, and Korea, where it is widely incorporated into both medicinal diets and daily cuisine. To address the lack of systematic research comparing raw and fried ZSS, this study aimed to elucidate the compositional and functional changes induced by the frying process. This study systematically compared the chemical profiles and antioxidant activities of ZSS and fried ZSS using ultra-performance liquid chromatography–quadrupole–time-of-flight mass spectrometry (UPLC–Q–TOF–MS) and gas chromatography–ion mobility spectrometry (GC–IMS). A total of 92 non-volatile compounds and 43 volatile organic compounds (VOCs) were identified. Frying significantly promoted the formation of polar compounds such as flavonoids and saponins and increased the content of aldehydes and alcohols, thereby generating aromas characteristic of Maillard reactions and lipid oxidation. Principal component analysis (PCA) and orthogonal partial least squares discriminant analysis (OPLS-DA) clearly distinguished the two groups in terms of their chemical composition and flavor characteristics. In addition, 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays demonstrated that the antioxidant capacity of fried ZSS was significantly higher than that of the raw sample (p < 0.05). These results indicate that the frying process reshapes the chemical properties and bioactivity of ZSS via multiple pathways, including glycoside hydrolysis, lipid oxidation, and Maillard reactions. Overall, this study establishes a scientific foundation for the development of functional foods derived from ZSS. Full article
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