Omics Strategies to Enhance Food Safety and Quality

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Quality and Safety".

Deadline for manuscript submissions: 28 February 2026 | Viewed by 644

Special Issue Editors


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Guest Editor
Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore 138673, Singapore
Interests: proteomics; metabolomics; food safety; mass spectrometry; foodomics

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Guest Editor
Department of Microbiology, ADA Forsyth Institute, Somerville, MA 02143, USA
Interests: proteomics; food safety; real-time detection; nanoparticles; food preservation

Special Issue Information

Dear Colleagues,

Omics technologies, including metabolomics, proteomics, transcriptomics, and genomics, have revolutionized our capacity to improve food safety and quality—these approaches provide a comprehensive understanding of food-related systems at the molecular level across various stages, including food processing/treatment, transportation, storage, and consumption, facilitating the detection of key markers and pathways linked to food contamination and spoilage. For instance, proteomics and metabolomics offer insights into changes in protein and chemical biomarkers for freshness, adulteration, and contamination, which also elucidates the antimicrobial mechanism of various treatments when applied to foodborne pathogens and spoilage organisms. Furthermore, integrating omics data with advanced computational tools makes it possible for prediction models of food quality and safety, contributing to improving the shelf life of perishable foods and monitoring the risks of foodborne diseases.

Therefore, this Special Issue welcomes both research papers and reviews on new applications related to omics strategies designed to enhance the safety and quality of food materials and food products.

Dr. Xiaowei Lou
Dr. Yuan Li
Guest Editors

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Keywords

  • omics strategies
  • metabolomics
  • proteomics
  • transcriptomics
  • genomics
  • food safety
  • food quality
 

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Published Papers (1 paper)

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Research

18 pages, 5999 KB  
Article
Metabolomics Analysis of the Spoilage Characteristics of Pseudomonas fragi and Aeromonas salmonicida Co-Culture in Refrigerated Grass Carp
by Yanlong Liu, Shuya Guo, Ruyan Xue, Li Liu, Abdul-Nabi Jatt and Caili Zhang
Foods 2025, 14(18), 3228; https://doi.org/10.3390/foods14183228 - 17 Sep 2025
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Abstract
Pseudomonas fragi and Aeromonas salmonicida are major spoilage microorganisms in refrigerated grass carp. This study systematically investigated the physicochemical and metabolomic characteristics of chilled grass carp that were artificially inoculated with P. fragi and A. salmonicida in mono- and co-culture. The results indicated [...] Read more.
Pseudomonas fragi and Aeromonas salmonicida are major spoilage microorganisms in refrigerated grass carp. This study systematically investigated the physicochemical and metabolomic characteristics of chilled grass carp that were artificially inoculated with P. fragi and A. salmonicida in mono- and co-culture. The results indicated that P. fragi was the dominant bacterium in the co-culture of grass carp. The P. fragi-inoculated group exhibited significantly higher levels of total volatile basic nitrogen and thiobarbituric acid reactive substances (TBARs, byproducts of lipid peroxidation) compared with the A. salmonicida group. Moreover, the TBAR levels were greater in the co-culture than in the A. salmonicida group at the end of storage. A metabolomic analysis revealed that 712, 424, and 465 differential metabolites were identified in grass carp inoculated with A. salmonicida, P. fragi, and their co-culture, respectively. The metabolic pathway enrichment showed that purine metabolism, aminoacyl-tRNA biosynthesis, glycerophospholipid metabolism, and amino acid metabolism were prevalent across all three inoculated groups. A total of 175 amino acids, peptides, and analogues were identified in the A. salmonicida group, indicating that A. salmonicida played a vital role in protein degradation. P. fragi was primarily enriched in linoleic acid metabolism and the biosynthesis of unsaturated fatty acids and fatty acids, demonstrating its advantages in lipid metabolism. Additionally, six potential spoilage biomarkers were identified, including inosine, cytidine, L-aspartic acid, L-tyrosine, Pro-Ile and PS(17:1(9Z)22:0). These results elucidated the complex and competitive interactions between A. salmonicida and P. fragi in the spoilage of grass carp, providing a scientific basis for the quality monitoring of grass carp and targeted preservation strategies. Full article
(This article belongs to the Special Issue Omics Strategies to Enhance Food Safety and Quality)
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