Nanofibrous Yarns and Nanotextiles for Biomedical Application

A special issue of Fibers (ISSN 2079-6439).

Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 2404

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Special Issue Editor


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Guest Editor
Center for Biomedical Innovation, Massachusetts Institute of Technology, Cambridge, MA 02139-4307, USA
Interests: nanotextiles; nanofibrous yarns; medical polymers; sutures; nanofibrous thread; electrospinning
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Special Issue Information

Dear Colleagues,

There is a growing interest in the field of medical textile technology with nanofibers. The enormous surface-to-volume ratio of medical nanotextiles enhances the biological interaction and provides numerous functional features which have never been explored before. The nanoscale properties of nanofibers and enhanced mechanical properties enable us to fabricate next-generation scaffolds for regenerative medicine.

Topics:

1) Nanotextiles for biomedical application;
2) Nano/microfibrous yarns for biomedical application;
3) Flexible, wearable fabrics for next-generation sensors;
4) Nanotextiles for drug delivery applications;
5) Nanotextiles for regenerative medicine.

Dr. John Joseph
Guest Editor

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Keywords

  • nanotextiles
  • nanofibrous yarns
  • medical polymers
  • sutures
  • nanofibrous thread
  • electrospinning

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Published Papers (1 paper)

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Research

21 pages, 5717 KiB  
Article
A Comparison of Chitosan Adhesion to KOH and H2O2 Pre-Treated Electrospun Poly(3-Hydroxybutyrate) Nanofibers
by Yansheng Zhou, Daqing Li, Xin Li, Ying Li, Bing Li and Fenglei Zhou
Fibers 2023, 11(11), 91; https://doi.org/10.3390/fib11110091 - 26 Oct 2023
Viewed by 1710
Abstract
Chitosan coatings could effectively increase the biostability and biocompatibility of biomaterials while maintaining their structural integrity. In this study, electrospun fibrous polyhydroxybutyrate (PHB) membranes were pre-treated with potassium hydroxide (KOH) or hydrogen peroxide (H2O2) and then modified with dopamine [...] Read more.
Chitosan coatings could effectively increase the biostability and biocompatibility of biomaterials while maintaining their structural integrity. In this study, electrospun fibrous polyhydroxybutyrate (PHB) membranes were pre-treated with potassium hydroxide (KOH) or hydrogen peroxide (H2O2) and then modified with dopamine (DA) and glutaraldehyde (GA) to improve their adhesion with chitosan (CS). Scanning electron microscopy (SEM), water contact angles (WCA), and Fourier transform infrared spectroscopy (FTIR) were used to demonstrate the successful generation of DA and GA-modified PHB fibers. KOH pre-treated PHB membranes exhibited superior binding efficiency with CS at low concentrations compared to their H2O2 pre-treated counterparts. The thermal analysis demonstrated a considerable decrease in the degradation temperature and crystallinity of KOH pre-treated membranes, with temperatures dropping from 309 °C to 265.5 °C and crystallinity reducing from 100% to 25.59% as CS concentration increased from 0 to 2 w/v%. In comparison, H2O2 pre-treated membranes experienced a mild reduction in degradation temperature, from 309 °C to 284.4 °C, and a large decrease in crystallinity from 100% to 43%. UV-vis analysis using Cibacron Brilliant Red 3B-A dye (CBR) indicated similar binding efficiencies at low CS concentrations for both pre-treatments, but decreased stability at higher concentrations for KOH pre-treated membranes. Mechanical testing revealed a considerable increase in Young’s modulus (2 to 14%), toughness (31 to 60%), and ultimate tensile stress (UTS) (14 to 63%) for KOH-treated membranes compared with H2O2 pre-treated membranes as CS concentration increased from 0 to 2 w/v%. Full article
(This article belongs to the Special Issue Nanofibrous Yarns and Nanotextiles for Biomedical Application)
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