Systems Metabolic Engineering for the Production of Value-Added Compounds
A special issue of Fermentation (ISSN 2311-5637). This special issue belongs to the section "Microbial Metabolism, Physiology & Genetics".
Deadline for manuscript submissions: 20 February 2026 | Viewed by 7
Special Issue Editors
Interests: heterologous biosynthesis; bioproducts; natural products; genetic engineering; metabolic engineering; bioprocess
Special Issues, Collections and Topics in MDPI journals
Interests: heterologous biosynthesis; bioproducts; natural products; genetic engineering; metabolic engineering; bioprocess
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Microorganisms play a vital role in modern life. Over the past decade, research into microbial fermentation for producing value-added compounds with nutritional, pharmaceutical and biofuel properties has grown increasingly sophisticated and widespread. The advances in genome sequencing and editing techniques together with synthetic biology tools have enabled researchers to identify the regulatory mechanisms underlying the overproduction of secondary metabolites and to monitor gene expression during the fermentation cycle, accelerating the rational application of metabolic pathway engineering.
For this Special Issue, we invite leading researchers and authors to submit their original research and review articles exploring the production of those value-added compounds from genetically engineered microbial strains (including Escherichia coli and Bacillus subtilis, Saccharomyces cerevisiae and Pichia pastoris, Streptomyces coelicolor and Streptomyces lividans, Aspergillus nidulans and Aspergillus oryzae, etc.). Papers focused on efforts to improve microbial strains and that address the complex problems of screening, advanced tools, and technology used for metabolic pathway rebuilding and fine-tuning, and new strategies for process optimization, are especially welcome to be submitted.
We particularly welcome submissions focused on:
- Strategies for microbial strain improvement and addressing complex challenges in screening;
- Advanced tools and technologies for metabolic pathway rebuilding and fine-tuning;
- Novel strategies for process optimization;
- Purification and Characterization of Metabolites
Dr. Guojian Zhang
Prof. Dr. Fu Yan
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fermentation is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- heterologous biosynthesis
- bioproducts
- natural products
- genetic engineering
- metabolic engineering
- bioprocess
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