Polycomb and Trithorax Group of Proteins in Development and Disease 2.0
A special issue of Epigenomes (ISSN 2075-4655).
Deadline for manuscript submissions: closed (30 June 2019) | Viewed by 14618
Special Issue Editor
Interests: cancer epigenetics; polycomb; chromatin remodeling; gene silencing; cellular differentiation; RNA modifications
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cellular identity and organism development are mediated by two large groups of proteins: the Polycomb group (PcG), which represses transcription, and the Trithorax group (TrxG), which activates transcription. The tight regulation and coordination of both protein families is fundamental to properly coordinate cellular programs that will enable development and differentiation. Deregulation of proteins belonging to PcG or TrxG families leads to a wide spectrum of developmental disorders and diseases, including cancer.
This Special Issue is focused on the function of PcG and TrxG complexes, both in development and disease. We will consider reviews, research, or method manuscripts of exceptional interest on the following topics:
- PcG or TrxG proteins in the development of any model organism;
- The role of PcG or TrxG components in disease;
- The role of PcG or TrxG in gene regulation and chromatin architecture.
Dr. Luciano Di Croce
Guest Editor
Manuscript Submission Information
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