Antimicrobial Resistance and Its Environmental Risk

A special issue of Environments (ISSN 2076-3298).

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1539

Special Issue Editors


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Guest Editor
Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, A.O.U. "G. Martino"-Torre Biologica 3°p, Via C. Valeria, s.n.c., 98125 Messina, Italy
Interests: environmental microbiology; antibiotic resistance in environmental matrices; prevention
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Guest Editor
Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, Via S. Sofia 87, 95123 Catania, Italy
Interests: prevention; public health; environmental microbiology

Special Issue Information

Dear Colleagues,

Antibiotic resistance, derived from resistance genes to synthetic and semi-synthetic antibiotics, spreads in the environment through multiple contamination routes, following different anthropic activities in which there is a high use of antibiotics. Resistance genes can reach the environment both through widespread sources of contamination (intensive agricultural areas, industrial districts, human activities distributed throughout the territory) and through single sources, such as intensive zootechnical plants, aquaculture, urban and hospital sewage, and commercial industries for the production of antibiotic substances.

The phenomenon is one of the main public health problems and has reached such proportions in recent years as to induce international and national institutions to raise the alarm and to promote initiatives aimed at its control. The latest European report on antibiotic resistance (ECDC, 2020) provided extremely worrying estimates: around 33,000 deaths a year are the direct consequence of resistant infections. To date, the commonly adopted strategy in human and veterinary medicine is the monitoring of antibiotic resistance in a selected group of bacterial species of clinical relevance. Although a "natural" resistance background is present in any bacterial community, the use–abuse of antibiotics in each sector (human, veterinary, agronomist) has determined the development and proliferation of specific resistance in bacterial communities exposed to the effects of human activities around the globe. The molecules not metabolized by the human body and the respective metabolites are excreted via urine and faeces, reaching urban wastewater and water purification plants, where they remain, even in minimal concentrations. Antibiotics and metabolites are then introduced into watercourses, lakes, or the sea through treated water, or into the soil through the use of purification sludge as fertilizer for fields.

The Special Issue that we propose has the purpose of gathering experiences in this area; new data on the subject will enrich those already in the scientific community. Studies carried out on classic and new environmental matrices involved in the spread of antibiotic resistance are encouraged.

Dr. Pasqualina Laganà
Dr. Maria Anna Coniglio
Guest Editors

Manuscript Submission Information

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Keywords

  • antibiotic-resistance
  • environmental matrices
  • environmental surveillance
  • prevention
  • risk assessment
  • advances in environmental diagnosis
  • innovative monitoring methods
  • new technologies

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Published Papers (1 paper)

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Research

21 pages, 6667 KiB  
Article
Assessing the Resilience of Enteric Bacteria in Manure in Response to Changes in Relative Humidity and UV-B Light
by Ingrid M. Leon, Brent W. Auvermann, Kevin Jack Bush, Kenneth Casey, William E. Pinchak, Javier Vinasco, Sara D. Lawhon, Jason K. Smith, Harvey Morgan Scott and Keri N. Norman
Environments 2024, 11(9), 197; https://doi.org/10.3390/environments11090197 - 10 Sep 2024
Viewed by 938
Abstract
Dehydrated manure from agricultural animal feedlots can become aerosolized and may potentially harbor viable antimicrobial-resistant bacteria. Little is known about the dynamics and risk of bacteria in bioaerosols originating from the feedyard environment. Nutrient deficiency, desiccation, UV exposure, temperature, and pH changes can [...] Read more.
Dehydrated manure from agricultural animal feedlots can become aerosolized and may potentially harbor viable antimicrobial-resistant bacteria. Little is known about the dynamics and risk of bacteria in bioaerosols originating from the feedyard environment. Nutrient deficiency, desiccation, UV exposure, temperature, and pH changes can affect bacterial viability. In this study, we investigated the impact of changes in relative humidity (RH) and UV-B exposure on enteric bacterial survival in vitro to simulate environmental conditions in cattle feedyards. Cattle manure samples were placed in two separate chambers with 73% RH and 31% RH, respectively. For the UV-B experiment, samples were placed in a chamber exposed to UV-B (treated) or in a chamber exposed to LED light (control). Samples from both experiments were spiral plated in triplicate onto selective agar media to quantify total aerobic bacteria, E. coli (total and antimicrobial-resistant (AMR)), and Enterococcus spp. (total and AMR). Results showed that enteric bacteria from cattle manure can withstand at least two stress conditions, including low RH levels and UV-B exposure. Moreover, the data revealed that antimicrobial-resistant bacteria can persist in manure under the harsh conditions that may be encountered in a feedyard environment. These findings underscore the need for mitigation strategies in feedlots to minimize the overall risk of bioaerosol formation. Full article
(This article belongs to the Special Issue Antimicrobial Resistance and Its Environmental Risk)
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