Molecular Diagnostics of Antimicrobial Resistance
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Diagnostic Microbiology and Infectious Disease".
Deadline for manuscript submissions: closed (31 August 2021) | Viewed by 20550
Special Issue Editors
Interests: molecular and epidemiological characterization of mechanisms of resistance to antibiotics in Gram-negatove pathogens; mobile genetic elements; beta-lactamases; beta-lactamase inhibitors; mechanisms of serine- and metallo-beta-lactamases
Special Issues, Collections and Topics in MDPI journals
Interests: enzymes; PCR; microbiology; cloning; biochemistry; electrophoresis; SDS-PAGE; protein expression; next generation sequencing; antibiotic resistance
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Antibiotic resistance is important for the national health system both in terms of economic impact and human sufferance. Epidemiological data are of primary importance to eventually identify new emerging resistance determinants in order to adapt antibiotic usage at the local level to limit therapeutic failures. Among Gram-negative and Gram-positive bacteria, Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter baumannii, Enterococcus spp, Staphylococcus aureus, and Streptococcus pneumonia are the main emergent pathogens. In these species, resistance may affect all major classes of antimicrobial agents such as β-lactams, fluoroquinolones, aminoglycosides, glycopeptide, etc. Many of these organism harbor antibiotic resistant genes (ARGs), eventually inserted into genetic mobile platforms (plasmids, transposons, integrons) able to move between different DNA molecules and transfer the genetic determinants in different bacteria species. Surveillance of antimicrobial resistance is critical to providing early warning of emerging problems, monitoring changing patterns of resistance, and targeting and evaluating prevention and control measures. The following topics will be considered:
- Molecular epidemiology of multidrug-resistant Gram-negative and Gram-positive bacteria;
- Diagnostics of mobile genetic elements with innovative molecular approaches;
- Role of beta-lactamases in antibiotic resistance.
Prof. Dr. Mariagrazia PerilliDr. Alessandra Piccirilli
Dr. Maria del Mar Tavìo-Perez
Guest Editors
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