Advances in Gastrointestinal Endoscopy for Diagnosis and Treatment

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Optical Diagnostics".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 6305

Special Issue Editors


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Guest Editor
1. Endoscopy Department, Cleveland Clinic London, London SW1X 7HY, UK
2. Gastroenterology Department, University Hospital of Larissa, 41334 Larissa, Greece
Interests: pancreatobiliary medicine; upper GI medicine; interventional endoscopy

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Guest Editor
1. Department of Gastroenterology, Hepatopancreatology and Digestive Oncology, Erasme University Hospital, Université Libre de Bruxelles, 1070 Brussels, Belgium
2. Department of Gastroenterology, General Hospital of Nea Ionia “Konstantopoulio-Patision”, Athens, Greece
Interests: interventional endoscopy; ERCP; EUS

Special Issue Information

Dear Colleagues,

Gastrointestinal Endoscopy has evolved in recent years, providing game-changing advantages in diagnosis and treatment by incorporating new devices, techniques and technological advances. The quality improvement in endoscopic views and the introduction of adjuvant tools, such as digital chromoendoscopy, endo-microscopy and artificial intelligence, have optimized visual diagnosis and targeted sampling in the broad field of luminal and pancreatobiliary pathologies. Moreover, the spectrum of therapeutic endoscopy has increased with new innovations which provide the potential for minimally invasive endo-surgical interventions from the esophagus to the rectum, including bariatrics, full thickness resections and pancreatobiliary interventions, even in patients with altered anatomy. This Special Issue aims to summarize the current diagnostic and therapeutic abilities and present the emerging approaches in GI endoscopy.

Dr. Apostolis Papaefthymiou
Dr. Paraskevas Gkolfakis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • endoscopy
  • artificial intelligence
  • interventional endoscopy
  • digital chromoendoscopy
  • therapeutic endoscopy

Published Papers (4 papers)

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Research

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11 pages, 9247 KiB  
Article
Feasibility and Efficacy of Gastric Underwater Endoscopic Mucosal Resection
by Dong Hyun Kim, Seon Young Park, Jin Won Kim and Hyun Soo Kim
Diagnostics 2024, 14(5), 536; https://doi.org/10.3390/diagnostics14050536 - 3 Mar 2024
Viewed by 1023
Abstract
Gastric cancer, a leading cause of cancer-related deaths globally, necessitates effective and early detection and treatment strategies. Endoscopic resection techniques, particularly endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD), have evolved significantly, enhancing the treatment of gastric neoplasms. Underwater endoscopic mucosal resection [...] Read more.
Gastric cancer, a leading cause of cancer-related deaths globally, necessitates effective and early detection and treatment strategies. Endoscopic resection techniques, particularly endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD), have evolved significantly, enhancing the treatment of gastric neoplasms. Underwater endoscopic mucosal resection (UEMR) is a widely used technique for the resection of duodenal and colorectal neoplasms. However, the feasibility and efficacy of UEMR in the stomach are not well established. This retrospective observational study, conducted at a tertiary medical center, evaluated the efficacy and safety of UEMR in 81 patients with gastric neoplasms. Thus, it indicates that UEMR is a highly effective and safe technique for managing small to medium-sized gastric neoplasms, achieving 100% en bloc and 93.8% R0 resection rates with a low incidence of complications. Moreover, the procedure time was found to be significantly shorter for UEMR compared to ESD, thus highlighting its efficiency. While UEMR demonstrates high safety and efficacy, it is not suitable for all patients, with some requiring conversion to ESD as a treatment option. Despite the promising results, broader validation through extensive and randomized trials is recommended to establish UEMR as a standard approach in gastric cancer management. Full article
(This article belongs to the Special Issue Advances in Gastrointestinal Endoscopy for Diagnosis and Treatment)
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Review

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10 pages, 615 KiB  
Review
Is Panenteric PillcamTM Crohn’s Capsule Endoscopy Ready for Widespread Use? A Narrative Review
by Alexandros Toskas, Faidon-Marios Laskaratos, Sergio Coda, Saswata Banerjee and Owen Epstein
Diagnostics 2023, 13(12), 2032; https://doi.org/10.3390/diagnostics13122032 - 12 Jun 2023
Cited by 3 | Viewed by 1303
Abstract
Patients diagnosed with Crohn’s disease are increasingly subjected to repeat colonoscopic and radiological examinations to assess the extent of the disease severity and the effects of treatment. PillcamTM Crohn’s video capsule, a modified colon capsule, was developed to generate a minimally invasive [...] Read more.
Patients diagnosed with Crohn’s disease are increasingly subjected to repeat colonoscopic and radiological examinations to assess the extent of the disease severity and the effects of treatment. PillcamTM Crohn’s video capsule, a modified colon capsule, was developed to generate a minimally invasive mouth to rectum video of the gastrointestinal tract. The capsule provides a wide-angle panoramic mucosal view to assess inflammation, ulceration, stenosis, disease extent, and effect of treatment. This review summarizes the evidence of its utility in both adult and paediatric Crohn’s disease and reviews the scoring systems used to quantify findings. The literature survey indicates that the PillcamTM Crohn’s capsule offers high sensitivity and specificity for the detection of inflammatory lesions and the extent and distribution of disease, and it could be considered a reliable imaging modality in both adults and childhood with Crohn’s disease. Full article
(This article belongs to the Special Issue Advances in Gastrointestinal Endoscopy for Diagnosis and Treatment)
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13 pages, 659 KiB  
Review
Endoscopic Ultrasound in the Diagnosis of Extrahepatic Cholangiocarcinoma: What Do We Know in 2023?
by Rares Ilie Orzan, Cristina Pojoga, Renata Agoston, Radu Seicean and Andrada Seicean
Diagnostics 2023, 13(6), 1023; https://doi.org/10.3390/diagnostics13061023 - 8 Mar 2023
Cited by 3 | Viewed by 2808
Abstract
Extrahepatic cholangiocarcinoma (CCA) is a rare and aggressive type of cancer, presenting as a mass or as a biliary stricture. This review summarizes the utility of endoscopic ultrasound (EUS) in the detection, staging, and determination of the differential diagnosis, especially when no cause [...] Read more.
Extrahepatic cholangiocarcinoma (CCA) is a rare and aggressive type of cancer, presenting as a mass or as a biliary stricture. This review summarizes the utility of endoscopic ultrasound (EUS) in the detection, staging, and determination of the differential diagnosis, especially when no cause of bile duct dilatation is revealed by cross-sectional imaging. The EUS detection rate for distal CCAs is higher than that for the proximal CCAs. The accuracy of T staging varies between 60 and 80%, and vascular involvement is correctly assessed by conventional EUS. EUS-tissue acquisition from the primary tumors is reserved for unresectable or metastatic CCA, especially in distal strictures or mass CCAs. For proximal lesions, EUS could be performed as an adjunctive to ERCP sampling when the latter is inconclusive. EUS is not appropriate for assessing the malignant features of lymph nodes in CCAs. Lymph node EUS-tissue acquisition should be performed only if it changes the surgical decision. Perhaps the development of EUS-fine needle biopsy and the detection of molecular genetic alteration will increase the diagnostic yield in CCAs. Full article
(This article belongs to the Special Issue Advances in Gastrointestinal Endoscopy for Diagnosis and Treatment)
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Other

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15 pages, 9416 KiB  
Case Report
Uncommon Presentation of Gastric Duplication Cyst with Left-Sided Portal Hypertension: A Case Report and Literature Review
by Adrian Boicean, Diana Prisca, Dan Georgian Bratu, Ciprian Ionut Bacila, Ciprian Tanasescu, Radu Chicea, Sorin Radu Fleaca, Sabrina Andreea Birsan, Cristian Ichim, Calin Ilie Mohor, Mihai Dan Roman, Adrian Nicolae Cristian, Samuel Bogdan Todor, Cosmin Ioan Mohor, Andrei Moisin and Adrian Hasegan
Diagnostics 2024, 14(7), 675; https://doi.org/10.3390/diagnostics14070675 - 22 Mar 2024
Viewed by 877
Abstract
Gastric duplication cysts (GDCs) in adults are exceedingly rare, with only a few documented cases in medical literature. The spectrum of clinical presentations varies widely, ranging from asymptomatic to severe symptoms such as hematemesis, vomiting or abdominal pain. Among the less common complications [...] Read more.
Gastric duplication cysts (GDCs) in adults are exceedingly rare, with only a few documented cases in medical literature. The spectrum of clinical presentations varies widely, ranging from asymptomatic to severe symptoms such as hematemesis, vomiting or abdominal pain. Among the less common complications associated with GDCs, segmental portal hypertension is a notable rarity. We present a compelling case report of a patient exhibiting signs of segmental portal hypertension, where ultrasound and echo-endoscopy revealed a sizable gastric duplication cyst as the underlying etiology. Recognizing the scarcity of literature on GDCs in adult patients, we conducted a thorough review to underscore the diagnostic significance of ultrasonography and endoscopic ultrasound (EUS) in accurately identifying these congenital anomalies. This case report and comprehensive literature review emphasize the pivotal role of EUS and abdominal ultrasound in achieving an accurate diagnosis of GDCs. By shedding light on the diagnostic and therapeutic intricacies, we aim to raise awareness among clinicians regarding this rare pathology and the importance of multimodal imaging approaches for optimal patient management. Full article
(This article belongs to the Special Issue Advances in Gastrointestinal Endoscopy for Diagnosis and Treatment)
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