Special Issue "Big Network Inference, Integration and Analysis for Precision Medicine (BigDataNetAnalysis)"
A special issue of Data (ISSN 2306-5729).
Deadline for manuscript submissions: 30 November 2019.
Precision Medicine is currently a hot research field and is of high interest for the bioinformatics community. The field attracts the interests of computer scientists, biologists, and medical doctors interested in its applications to biology, precision medicine, and pharmacology.
The rationale underlying the research is that many biological processes in different fields, from molecular biology to neurological sciences, may be elucidated only by considering mutual interactions among different players. For instance, the regulation of messenger RNA (mRNA) levels is due to the synergistic and antagonist actions of transcription factors (TFs) and microRNAs (miRNAs).
Similarly, network-based approaches have recently been applied to modeling the human brain. A common aspect of these different scenarios is that available technological platforms enable the investigation of only a single aspect of these mechanisms, that is, the quantification of levels of mRNA or miRNA or the investigation of the activity of single brain regions.
Consequently, a comprehensive and holistic analysis is made possible only by the integration of these data sources. Currently, the interest of researchers in this area is growing, the number of projects is increasing, and the number of challenges and issues for computer scientists is considerable. Many approaches are based on the use of results coming from graph theory; thus, the need for a workshop bringing together computer scientists and biologists/doctors arises.
Recent approaches have integrated big data in heterogeneous networks. This workshop solicits submissions discussing general concepts related to improvements and challenges in this field. In addition, surveys or positions on data integrations, as well as novel approaches of analysis are welcome.
This Special Issue of Data is dedicated to selected and extended papers from the BigDataNetAnalysis Workshop, which is in conjunction with BIBM 2018 conference held in Madrid, Spain, 3–6 December 2018.
Dr. Pietro Hiram Guzzi
Dr. Laura Antonelli
Dr. Swarup Roy
Dr. Pierangelo Veltri
Manuscript Submission Information
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