Circulating Tumor Cells (CTCs): Current and Emerging Utility in Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".
Deadline for manuscript submissions: closed (31 March 2025) | Viewed by 1889
Special Issue Editors
Interests: 3D models; senescence; cancer; therapy resistance; metabolism; extracellular matrix (ECM)
Special Issues, Collections and Topics in MDPI journals
Interests: molecular characterization; circulating tumor cells; new methods development
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
CTCs are a rare population of cells shed in the bloodstream by primary epithelial tumors that move towards distant organs to generate metastasis. In a translational context, CTC enumeration, detection and characterization (at both phenotypic and molecular levels) were proven to have a clinical significance, especially in early epithelial cancer detection and prognosis prediction. Given their availability in the peripheral blood, CTC analysis allows also for therapy response and minimal residual disease (MRD) monitoring. However, the discovery of new CTC markers in different cancer types is a critical step in developing new methods for CTC detection and improving recovery. Furthermore, thanks to CTCs in vitro culturing it is possible to increase their numbers, simplifying the analysis of their biological and molecular features and allowing for a deeper comprehension of the nature of tumors.
Topics of this Special Issue can include but are not limited to:
- CTC biology;
- Tumor progression;
- Minimal residual disease (MRD);
- Therapy response monitoring;
- Metastatic organotropism;
- New methods for CTC detection and characterization;
- CTC-derived in vitro models.
Dr. Michele Zanoni
Guest Editor
Dr. Tania Rossi
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- circulating tumor cells (CTC)
- tumor progression
- therapy response
- metastatic
- novel methods
- in vitro
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
