Optimizing Surgical Management for Gynecologic Cancers

A special issue of Current Oncology (ISSN 1718-7729). This special issue belongs to the section "Gynecologic Oncology".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 2638

Special Issue Editor


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Guest Editor
Department of Obstetrics and Gynecology, Schulich Medicine and Dentistry, Western University, London, ON N6A 5C1, Canada
Interests: gynaecology; cancer; surgical care women

Special Issue Information

Dear Colleagues,

The surgical management of gynecologic malignancies is the backbone of the specialty of gynecologic oncology. Where radicality of treatment was once one of the hallmarks of the specialty, more nuanced approaches now abound. These strategies/techniques maintain or improve outcomes while minimizing toxicity and enhancing the surgical experience.

This Special Issue will feature original research, reviews, and novel case reports that move the knowledge base forward towards, realizing better outcomes in the management of gynecologic malignancy. This includes new surgical approaches, pre-operative optimization, peri-operative innovations to enhance surgical recovery, de-escalation strategies, evaluations of new technology in the surgical setting, and implementation of novel service delivery models to enable surgical planning.

Dr. Jacob D. McGee
Guest Editor

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Keywords

  • pre-operative optimization
  • de-escalation
  • surgical approach
  • risk stratification
  • quality of Life
  • novel techniques

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Published Papers (2 papers)

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Review

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15 pages, 398 KiB  
Review
Multimodal Prehabilitation for Gynecologic Cancer Surgery
by Jeongyun Kim, Chae Hyeong Lee and Ga Won Yim
Curr. Oncol. 2025, 32(2), 109; https://doi.org/10.3390/curroncol32020109 - 14 Feb 2025
Cited by 1 | Viewed by 857
Abstract
Surgical treatment is commonly employed to treat patients with gynecologic cancer, although surgery itself may function as a stressor, reducing the patients’ functional capacity and recovery. Prehabilitation programs attempt to improve patients’ overall health and baseline function prior to surgery, thereby enhancing recovery [...] Read more.
Surgical treatment is commonly employed to treat patients with gynecologic cancer, although surgery itself may function as a stressor, reducing the patients’ functional capacity and recovery. Prehabilitation programs attempt to improve patients’ overall health and baseline function prior to surgery, thereby enhancing recovery and lowering morbidity. In recent years, prehabilitation has come to primarily refer to multimodal programs that combine physical activity, nutritional support, psychological well-being, and other medical interventions. However, the specific methods of implementing prehabilitation and measuring its effectiveness are heterogeneous. Moreover, high-level evidence regarding prehabilitation in gynecologic cancer surgery is limited. This review provides a summary of multimodal prehabilitation studies in gynecologic oncologic surgery. Enhanced postoperative recovery, lower postoperative complications, lower rate of blood transfusions, and faster gastrointestinal functional recovery have been reported after multimodal prehabilitation interventions. Patients and healthcare professionals should recognize the importance of prehabilitation in the field of gynecologic oncologic treatment, based on the emerging evidence. In addition, there is a need to establish an appropriate target group and construct a well-designed and tailored prehabilitation program. Full article
(This article belongs to the Special Issue Optimizing Surgical Management for Gynecologic Cancers)
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Other

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14 pages, 905 KiB  
Systematic Review
The Importance of Patient-Reported Outcome Measures (PROMs) in Oncological Vulvoperineal Defect Reconstruction: A Systematic Review
by Nicole E. Speck, Julia Stoffel, Séverin Wendelspiess, Christian Appenzeller-Herzog, Kristin M. Schaefer, Loraine P. Kouba, Florian Rüter, Céline Montavon, Viola Heinzelmann-Schwarz, Martin D. Haug, Dirk J. Schaefer, Tarek Ismail and Elisabeth A. Kappos
Curr. Oncol. 2024, 31(10), 6300-6313; https://doi.org/10.3390/curroncol31100470 - 18 Oct 2024
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Abstract
Background: Patient-reported outcome measures (PROMs) have gained increased importance in assessing outcomes after reconstructive surgery. This also applies to the reconstruction of vulvoperineal defects after resection of gynecological or colorectal cancers in women. The objective of this study is to analyze the current [...] Read more.
Background: Patient-reported outcome measures (PROMs) have gained increased importance in assessing outcomes after reconstructive surgery. This also applies to the reconstruction of vulvoperineal defects after resection of gynecological or colorectal cancers in women. The objective of this study is to analyze the current state of PROM tool use within this patient population. Methods: By systematic literature searches in Embase, Medline, and Web of Science, English-language studies published after 1980, including randomized controlled trials, cohort studies, and case series reporting on vulvoperineal defect reconstruction, which were included if they also analyzed quality of life (QoL) and/or PROMs. The PROM tools used by each study were extracted, analyzed, and compared. Results: The primary search yielded 2576 abstracts, of which 395 articles were retrieved in full text. Of these, 50 reported on vulvoperineal defect reconstruction, among which 27 studies analyzing QoL were found. Of those, 17 met the inclusion criteria for this systematic review. After full-text screening, 14 different PROM tools and 5 individual, non-standardized questionnaires were identified. Only 22% of studies used a validated PROM tool. Conclusion: Far too few studies currently use PROM tools to assess outcomes in oncological vulvoperineal defect reconstruction. Less than half of the used PROMs are validated. No PROM was designed to specifically measure QoL in this patient population. The standardized implementation of a validated PROM tool in the clinical treatment of this patient population is an essential step to improve outcomes, enable the comparison of research, and support evidence-based treatment approaches. Full article
(This article belongs to the Special Issue Optimizing Surgical Management for Gynecologic Cancers)
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