- Review
Comparative Characterization of High-Grade Glioma Models in Rats: Its Importance for Neurobiology
- Vera Vladimirovna Kudelkina,
- Alexandra Igorevna Bulava,
- Alexander Georgievich Gorkin,
- Yana Andreevna Venerina and
- Yuri Iosifovich Alexandrov
The high attrition rates in glioblastoma (GB) therapeutic development stem largely from preclinical models that fail to adequately recapitulate the dynamic tumor–host ecosystem. Unlike previous reviews that characterize glioma cell lines in iso...

