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  • Review
  • Open Access
137 Views
19 Pages

Comparative Characterization of High-Grade Glioma Models in Rats: Its Importance for Neurobiology

  • Vera Vladimirovna Kudelkina,
  • Alexandra Igorevna Bulava,
  • Alexander Georgievich Gorkin,
  • Yana Andreevna Venerina and
  • Yuri Iosifovich Alexandrov

The high attrition rates in glioblastoma (GB) therapeutic development stem largely from preclinical models that fail to adequately recapitulate the dynamic tumor–host ecosystem. Unlike previous reviews that characterize glioma cell lines in iso...

  • Brief Report
  • Open Access
268 Views
13 Pages

Promoting Brain Health: Report on Activities of the Bern Brain Health Working Group

  • Tobias Monschein,
  • Iris-Katharina Penner,
  • Irina Filchenko,
  • Albrecht P. A. Vorster,
  • Hakan Sarikaya,
  • Gian Luca Di Tanna,
  • Mirjam R. Heldner,
  • Bogdan Draganski,
  • Kristina Adorjan and
  • Simon Jung
  • + 3 authors

Brain Health has become a global public health priority, driven mainly by the rapid aging of populations and the increasing burden of neurological and psychiatric disorders. This report presents the first activities of the Bern Brain Health Working G...

  • Article
  • Open Access
881 Views
16 Pages

Working Memory Training Improves Cognitive and Clinical ADHD Symptoms in Children

  • Maha S. Alsaad,
  • Abeer F. Almarzouki,
  • Solafa H. Ghoneim,
  • Basma A. Al-Jabri and
  • Samraa Suliman

Working memory training (WMT) has promising effects on cognitive and clinical outcomes in children with attention deficit hyperactivity disorder (ADHD). However, few studies have explored the effectiveness of such programs in developing countries wit...

  • Brief Report
  • Open Access
193 Views
9 Pages

Impact of Daytime Versus On-Call Admission on Outcomes in Geriatric Traumatic Brain Injury: A Retrospective Analysis from a Neurotrauma Center

  • Anas Zaman,
  • Yasmine Albalushi,
  • Hashim Alibrahim,
  • Sameh Almatroushi,
  • Mahmood Alnoufali,
  • Kawthar Almaknena and
  • Tariq D Al-Saadi

Background: Traumatic Brain Injury (TBI) represents a growing cause of medical emergencies globally. Objective: This study evaluates whether healthcare outcomes for TBI patients differ between daytime and on-call (after-hours) admissions. Methods: A...

  • Review
  • Open Access
667 Views
28 Pages

Evolution of Pharmacologic Induction of Burst Suppression in Adult TBI: Barbiturate Coma Versus Modern Sedatives

  • Đula Đilvesi,
  • Teodora Tubić,
  • Sanja Maričić Prijić and
  • Jagoš Golubović

Background: Severe traumatic brain injury (TBI) often leads to elevated intracranial pressure (ICP) that requires aggressive management. Inducing burst suppression with deep sedation is an established therapy for refractory intracranial hypertension....

  • Article
  • Open Access
363 Views
12 Pages

Background and Objectives: The mechanisms of traumatic brain injury (TBI), patient characteristics, and long-term outcomes in elderly patients differ from those in other age groups. This study aims to evaluate the effectiveness of the Elderly Traumat...

  • Review
  • Open Access
1,356 Views
20 Pages

Bridging Imaging and Therapy: A Review of Advances in Neuroradiology and Neuro-Oncology

  • Venkatraman Pitchaikannu,
  • Subramani Vellaiyan,
  • Shweta Kedia,
  • Vivek Tandon,
  • Rajinder Kumar,
  • Deepak Agarwal,
  • Manoj Phalak,
  • Satish Kumar Verma,
  • Dattaraj P. Sawarkar and
  • Kanwaljeet Garg
  • + 1 author

Neuroradiology and neuro-oncology are rapidly emerging fields in the diagnosis and treatment of central nervous system (CNS) diseases, including brain tumors. This review presents a comprehensive look at the current imaging techniques, clinical appli...

  • Perspective
  • Open Access
714 Views
12 Pages

Neurorehabilitation as a Cornerstone of the Brain Health Plan

  • Karsten Krakow,
  • Paolo Rossi,
  • Arseny A. Sokolov,
  • Matthias Elstner,
  • Rene M. Müri and
  • Daniel Zutter

Background: Neurorehabilitation plays a central role in restoring and maintaining brain health across lifespan. However, its contribution is often underestimated in public health policies. Aim: This paper aims to highlight the importance of neuroreha...

  • Article
  • Open Access
2,391 Views
28 Pages

Background: Deep vein thrombosis (DVT) is a serious thromboinflammatory complication of acute ischemic stroke (AIS). The true incidence, mechanistic risk factors, and optimal prophylactic strategies remain uncertain, particularly in the era of reperf...

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Clin. Transl. Neurosci. - ISSN 2514-183X