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  • 5.2
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  • 14 days
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Computation

Computation is a peer-reviewed journal of computational science and engineering published monthly online by MDPI. 

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All Articles (1,819)

  • Review
  • Open Access

Epilepsy digital twins require patient-specific computational models that evolve with longitudinal observations and support prospective inference. We conducted a scoping review of complementary patient-specific modeling and longitudinal or remote EEG approaches, searching five databases with a publication cutoff of 26 August 2026. Additional retrieval on 11 October 2026 yielded 42 of the 54 previously unavailable reports. Following consistent eligibility reassessment, 68 reports were included, 22 were excluded after full-text assessment, and 12 remained unretrieved. Fourteen included reports were classified as C0, ten as C1, forty as C2, three as C3, and one as C4 using a review-specific functional framework. Three reports demonstrated repeated updating with prospective prediction or simulation, and one demonstrated experimental governed feedback. This combined count does not establish four longitudinally updated digital twins. No included report demonstrated the complete non-invasive longitudinal architecture of observation, explicit patient representation, repeated updating, uncertainty-aware prospective inference, and governed output. Mechanistic and dynamic network models contributed individualized representations, while remote EEG and adaptive computation contributed observation and prediction. Initial personalization was more common than repeated updating. The original single-reviewer workflow was supplemented by separate coauthor review of selection and functional classification. Incomplete retrieval, omitted Embase coverage, interpretive coding boundaries, and non-harmonized clinical descriptors still limit interpretation. Functional codes do not establish etiological applicability or treatment benefit. Progress requires population-specific, prospective validation of integrated architectures.

Computation

15 October 2026

Conceptual architecture for a longitudinal epilepsy digital twin. Longitudinal EEG informs an individualized dynamical model from which states, network properties, biomarkers, and predictions can be derived. Model outputs may support localization, forecasting, treatment selection, and eventually governed intervention. Subsequent EEG and clinical observations provide feedback for model updating. Forward arrows indicate information flow, and the return arrow represents feedback for model updating. Colors distinguish conceptual components and illustrative brain features; they have no quantitative scale. The diagram is a proposed integration architecture, not a system demonstrated by an included study. The state-space equations are illustrative, and the listed interventions are potential applications whose effectiveness was not evaluated in this review.
  • Feature Paper
  • Article
  • Open Access

The increasing electricity demand of educational buildings requires the development of intelligent approaches to power supply management that improve energy efficiency and ensure the reliable operation of electrical networks. This study aims to develop a mathematical model for determining the recommended voltage level in the power supply system of an educational building and implement it in a PLC-based SCADA control system. A second-order central composite design was applied to investigate the influence of three factors, including total electrical load, building wiring length, and external supply line length, on the recommended voltage level. The regression model was statistically validated using Cochran’s, Student’s, and Fisher’s criteria. The obtained model demonstrated high adequacy for the experimental data (R2 = 0.9934, adjusted R2ad = 0.9884, RMSE = 0.447 kV, and F = 0.175 < Fcr = 2.30). The developed algorithm was implemented in the OWEN PLC300 controller using the EnLogic programming environment and integrated with the ENTEK SCADA system for automated voltage calculation and load management according to consumer priority. The proposed methodology can be applied in the design and modernisation of automated power supply systems for educational buildings and provides a practical approach to improving the efficiency of electrical energy distribution.

Computation

13 October 2026

ENTEK SCADA operator interface for monitoring the electrical distribution system and displaying the recommended voltage level in educational building No. 8.
  • Review
  • Open Access

Computational modeling has become an important tool for investigating complex cardiovascular conditions and supporting the development and evaluation of endovascular treatments. In thoracic aortic disease, numerical approaches provide tools for examining the interaction between blood flow, arterial mechanics, and implanted stent-grafts under physiologically relevant conditions. This study reviews the application of computational methods to thoracic endovascular aortic interventions, considering the main approaches used to investigate their hemodynamic, structural, and biomechanical behavior. The database was retrieved from the Web of Science on 20 March 2026, yielding a total of 99 records, of which 94 were retained. A bibliometric analysis is first presented to quantify the available literature, characterizing the evolution of the field, major research directions, and methodological developments. Then, the literature is discussed with a focus on the capabilities of computational methodologies, particularly computational fluid dynamics, the finite element method, and fluid–structure interaction. The literature shows a growth in computational investigations, with computational fluid dynamics being the most frequently employed approach, complemented by finite element and fluid–structure interaction methods. The representative studies examined also illustrate the development of patient-specific and multiphysics approaches alongside more conventional computational models. These developments have expanded the potential of computational simulations for studying disease progression, device performance, treatment strategies, and post-intervention outcomes. However, challenges related to computational cost, physiological boundary conditions, material properties, model assumptions, and experimental or clinical validation remain.

Computation

13 October 2026

Flow diagram summarizing the literature search and selection process based on the PRISMA framework.
  • Article
  • Open Access

In this study, an integrated finite-difference and deep neural network analysis of the simultaneous multiphysics of coupled momentum, heat, nanoparticle, and pollutant transport in a Sutterby tri-hybrid nanofluid over a quadratically radiative Riga surface is developed. The Fe3O4, Al2O3, and TiO2 nanoparticles are considered, and a mixture of propylene glycol and water is used, along with electroosmotic forcing, electromagnetic actuation, nonlinear thermal radiation, viscous dissipation, Brownian motion, thermophoresis, and pollutant transport. The key novelty is the ability to formally connect these strongly coupled nonlinear transport processes with a deep neural network (DNN) surrogate model to allow for the rapid and accurate prediction of complex thermo-fluid and mass-transfer responses. The governing equations are then transformed into nonlinear equations and solved numerically using a finite difference method (FDM) coded in FORTRAN to produce high fidelity numerical data sets that are used to train a feed-forward back-propagation deep neural network (DNN) implemented in Python with PyTorch. The optimized DNN successfully predicted the velocity, temperature, field of nanoparticles, and pollutant concentration, with the RMSE less than (3.2 × 10−2) and (R2 > 0.987), which indicates that the optimized DNN possesses high predictive accuracy and reliability. The fluid motion is improved by the increased electroosmotic and electromagnetic parameters due to increased electrokinetic and Lorentz forces, and the increased Brinkman number increases the fluid viscous dissipation heating and raises the temperature field. The enhanced Brownian motion facilitates the migration of nanoparticles and greatly affects coupled heat and mass transport while pollutant-related parameters control concentration distributions. The proposed DNN framework has the potential of being an efficient surrogate for fast simulations, parametric evaluation, and optimization for nonlinear multiphysics systems, and has direct applications to thermal management systems in industry, microfluidic processing, electrochemical technologies, electromagnetic flow-control devices, industrial wastewater treatment systems, and pollutant removal systems.

Computation

11 October 2026

(a) Schematic illustration of the potential applications of the proposed Fe3O4–Al2O3–TiO2/50:50 propylene glycol–water Sutterby tri-hybrid nanofluid. (b) Physical model and coordinate system.

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Editors: Shi Cheng, Chaomin Luo, Shangce Gao
Nonlinear System Modelling and Control
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Nonlinear System Modelling and Control

Editors: Chathura Wanigasekara
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Computation - ISSN 2079-3197