Phenolic Compounds: Extraction, Chemical Profiles, and Bioactivity

Dear Colleagues,

Phenolic compounds represent one of the most diverse and bioactive classes of secondary plant metabolites, widely recognized for their antioxidant, anti-inflammatory, antimicrobial, and therapeutic properties. In recent years, advances in extraction technologies, sustainable sourcing strategies, and analytical methods have significantly expanded our understanding of phenolic compounds, both in their natural matrices and as functional ingredients in food, pharmaceutical, and environmental applications.

This Special Issue aims to provide an updated, multidisciplinary perspective on the extraction, chemical profiling, and bioactivity of phenolic compounds. Particular emphasis will be placed on innovative, eco-friendly extraction methods, such as ultrasound-assisted extraction and the use of natural deep eutectic solvents, as well as the valorization of agro-industrial by-products as sustainable sources of phenolics. Contributions addressing the structural characterization and comprehensive chemical profiling of phenolic compounds using advanced chromatographic and spectrometric techniques are especially welcome.

Furthermore, the issue aims to highlight new findings on the health-promoting effects of phenolic compounds and their role as natural preservatives in food systems. Emerging topics, such as the environmental fate and atmospheric interactions of phenolics, as well as the development of functional foods enriched with these bioactive molecules, are also of interest.

This Special Issue offers a platform for researchers to share original research articles and reviews that advance the current knowledge on phenolic compounds, from sustainable extraction to bioactivity validation and functional applications.

Dr. Francisco Vázquez-Armenta
Dr. Ariadna Thalia Bernal-Mercado
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Compounds is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.