Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
2.9
2.8
Journals
CIMB
Special Issues
The 25th Anniversary of CIMB: Perspectives in Molecular Biology
cimb-logo
Submit to CIMB Review for CIMB Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

The 25th Anniversary of CIMB: Perspectives in Molecular Biology

A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Biochemistry, Molecular and Cellular Biology".

Deadline for manuscript submissions: closed (31 December 2024) | Viewed by 7061

Special Issue Editors

Prof. Dr. Madhav Bhatia

E-Mail Website
Guest Editor
Department of Pathology and Biomedical Science, University of Otago, Christchurch, 2 Riccarton Avenue, P.O. Box 4345, Christchurch 8140, New Zealand
Interests: inflammation; acute pancreatitis; sepsis; burn injury; arthritis; hydrogen sulfide; substance P; chemokines; leukocytes
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Ru Chih C. Huang

E-Mail Website
Guest Editor
1. Department of Biology, Zanvyl Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD 21218-2685, USA
2. National Academy of Inventors, Tampa, FL 33612, USA
3. Academia Sinica, 128 Academia Road, Section 2, Nankang, Taipei 11529, Taiwan
Interests: chromatin structure and function; tetra-O-methyl nordihydroguaiaretic acid (M4N, terameprocol); oncogenic development in humans; chemotherapeutic drug treatments; viral replication; gene functions
Special Issues, Collections and Topics in MDPI journals
Dr. Hidayat Hussain

E-Mail Website
Guest Editor
Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle (Saale), Germany
Interests: natural product; chemistry; medicinal chemistry; cancer biology; bioorganic chemistry; pharmacology; diabetes; synthetic chemistry; biology oriented synthesis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This year (2024), we are celebrating the 25th Anniversary of Current Issues in Molecular Biology (CIMB, ISSN 1467-3045). Hence, we are organizing a Special Issue to commemorate this important milestone.

Current Issues in Molecular Biology was launched in 1999 and has published international and multidisciplinary articles on all aspects of molecular biology spanning from basic mechanisms to applications in fields primarily, but not exclusively, relevant to microbiology and virology. Current Issues in Molecular Biology, published by Caister Academic Press from 1999-2021, is the home of 388 peer-reviewed articles across 42 volumes. As of 5 March 2021, Current Issues in Molecular Biology joined the group of journals published by MDPI.

During the past 25 years, CIMB has significantly contributed to scientific advancements in the multidisciplinary field of molecular biology. As such, CIMB will continue to serve as a forum wherein novel discoveries are widely shared with the scientific community and the general public at large.

To help celebrate this important event, we warmly invite you to submit original research papers, comprehensive review articles, and/or short communications from research that addresses relevant aspects of molecular biology, molecular plant sciences, molecular microbiology, molecular medicine and so on for peer review and possible publication in this Special Issue. We expect that this Special Issue will attract considerable attention, as we prepare to celebrate the excellent scientific contributions of CIMB from the past 25 years.

Prof. Dr. Madhav Bhatia
Prof. Dr. Ru Chih C. Huang
Dr. Hidayat Hussain
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecular biology
  • molecular plant sciences
  • molecular microbiology
  • molecular medicine
  • molecular pharmacology

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (5 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Editorial

Jump to: Research, Review

3 pages, 150 KiB  
Editorial
The 25th Anniversary of Current Issues in Molecular Biology: Marking This Significant Milestone
by Madhav Bhatia
Curr. Issues Mol. Biol. 2024, 46(12), 14321-14323; https://doi.org/10.3390/cimb46120858 - 19 Dec 2024
Viewed by 984
Abstract
Current Issues in Molecular Biology (CIMB) (https://www [...] Full article
(This article belongs to the Special Issue The 25th Anniversary of CIMB: Perspectives in Molecular Biology)

Research

Jump to: Editorial, Review

9 pages, 1666 KiB  
Article
The Electric Field Guided HaCaT Cell Migration Through the EGFR/p38 MAPK/Akt Pathway
by Huajian Zhou, Shihao Zhang, Xiaoli Jin, Chunxian A, Peng Gong and Sanjun Zhao
Curr. Issues Mol. Biol. 2025, 47(1), 16; https://doi.org/10.3390/cimb47010016 - 31 Dec 2024
Cited by 1 | Viewed by 860
Abstract
Previous studies have shown that the endogenous electric field (EF) is an overriding cure in guiding cell migration toward the wound center to promote wound healing, but the mechanism underlying is unclear. In this study, we investigated the molecular mechanism of electric field-guided [...] Read more.
Previous studies have shown that the endogenous electric field (EF) is an overriding cure in guiding cell migration toward the wound center to promote wound healing, but the mechanism underlying is unclear. In this study, we investigated the molecular mechanism of electric field-guided cell migration in human keratinocyte HaCaT cells. Our results showed that HaCaT cells migrate toward the anode under EFs. The phosphorylation levels of p38 MAPK and Akt were obviously elevated in the EF. Knocking down p38 MAPK obviously abolished directed migration of HaCaT cells under the EFs. Inhibiting p38 MAPK by SB203580 impaired the EF-guided cell migration. The electric field may guide HaCaT cell migration through the EGFR/p38 MAPK/Akt pathway. Full article
(This article belongs to the Special Issue The 25th Anniversary of CIMB: Perspectives in Molecular Biology)
►▼ Show Figures

Figure 1

16 pages, 3422 KiB  
Article
Evidence to Support the Collaboration of SP1, MYC, and HIF1A and Their Association with microRNAs
by Jong Ho Chun, Kotohiko Kimura, Monika Rajput, Ming-Hua Hsu, Yu-Chuan Liang, Akanksha Ramadas Shanbhag, Pei-Ju Chiang, Tiffany L. B. Jackson and Ru Chih C. Huang
Curr. Issues Mol. Biol. 2024, 46(11), 12481-12496; https://doi.org/10.3390/cimb46110741 - 5 Nov 2024
Viewed by 1913
Abstract
This study provides evidence to support the concept proposed by Kimura et al. in 2023 that the inhibitors of SP1, MYC, and HIF1A should induce strong anticancer activity by reducing the expression of stem cell-related proteins. In LN229 and U87MG glioblastoma cells, either [...] Read more.
This study provides evidence to support the concept proposed by Kimura et al. in 2023 that the inhibitors of SP1, MYC, and HIF1A should induce strong anticancer activity by reducing the expression of stem cell-related proteins. In LN229 and U87MG glioblastoma cells, either tetra-methyl-O-nordihydroguaiaretic acid (M4N) or tetra-acetyl-O-nordihydroguaiaretic acid (A4N) suppressed SP1 and only a few stem cell-related proteins and induced only a small amount of cell death; in contrast, the combination treatment of M4N with A4N greatly suppressed the expression of SP1, MYC, and HIF1A, as well as all of the stem cell-related proteins examined, and greatly induced cell death. The bioinformatic analysis showed that the proteins associated with SP1, MYC, and HIF1A were specifically involved in the regulation of transcription and that various microRNAs (miRNAs) that had been shown to induce either anti- or procancer activity were associated with SP1, MYC, and HIF1A, which suggested that the inhibition of SP1, MYC, and HIF1A could modulate the transcription of both coding and noncoding RNAs and affect cancers. These data overall supported our concept. Full article
(This article belongs to the Special Issue The 25th Anniversary of CIMB: Perspectives in Molecular Biology)
►▼ Show Figures

Figure 1

Review

Jump to: Editorial, Research

18 pages, 1324 KiB  
Review
SARS-CoV-2 and Environmental Changes: The Perfect Storm
by Mario Caldarelli, Pierluigi Rio, Vincenzo Giambra, Ivana Palucci, Antonio Gasbarrini, Giovanni Gambassi and Rossella Cianci
Curr. Issues Mol. Biol. 2024, 46(11), 11835-11852; https://doi.org/10.3390/cimb46110703 - 23 Oct 2024
Viewed by 1269
Abstract
The COVID-19 pandemic has had a significant impact on the global economy. It also provided insights into how the looming global climate crisis might be addressed, as there are several similarities between the challenges proposed by COVID-19 and those expected from the coming [...] Read more.
The COVID-19 pandemic has had a significant impact on the global economy. It also provided insights into how the looming global climate crisis might be addressed, as there are several similarities between the challenges proposed by COVID-19 and those expected from the coming climate emergency. COVID-19 is an immediate health threat, but climate change represents a more gradual and insidious risk that will lead to long-term consequences for human health. Research shows that climate change, air pollution and the pandemics have a negative impact on health. Recent studies show that COVID-19 mortality increases with climate extremes. The goal of our review is to analyze the clinical findings of COVID-19 and how they are affected by the climate change, while also providing insight into the emergence of new variants and their ability to evade the immune system. We selected and synthesized data from primary studies, reviews, meta-analyses, and systematic reviews. Selection was based on rigorous methodological and relevance criteria. Indeed, a new variant of SARS-CoV-2, named JN.1, has emerged as the dominant, first in the United States and then worldwide; the variant has specific mutations in its spike proteins that increase its transmissibility. According to the World Health Organization (WHO), JN.1 is currently the most reported variant of interest (VOI), having been identified in 132 countries. We highlight the link between climate change and pandemics, emphasizing the need for global action, targeted medical approaches and scientific innovation. Full article
(This article belongs to the Special Issue The 25th Anniversary of CIMB: Perspectives in Molecular Biology)
►▼ Show Figures

Figure 1

20 pages, 854 KiB  
Review
The Microbiota in Cancer: A Secondary Player or a Protagonist?
by Ana María Gómez García, Francisco López Muñoz and Eduardo García-Rico
Curr. Issues Mol. Biol. 2024, 46(8), 7812-7831; https://doi.org/10.3390/cimb46080463 - 23 Jul 2024
Viewed by 1305
Abstract
The intestinal microbiota and the human body are in a permanent interaction. There is a symbiotic relationship in which the microbiota plays a vitally important role in the performance of numerous functions, including digestion, metabolism, the development of lymphoid tissue, defensive functions, and [...] Read more.
The intestinal microbiota and the human body are in a permanent interaction. There is a symbiotic relationship in which the microbiota plays a vitally important role in the performance of numerous functions, including digestion, metabolism, the development of lymphoid tissue, defensive functions, and other processes. It is a true metabolic organ essential for life and has potential involvement in various pathological states, including cancer and pathologies other than those of a digestive nature. A growing topic of great interest for its implications is the relationship between the microbiota and cancer. Dysbiosis plays a role in oncogenesis, tumor progression, and even the response to cancer treatment. The effect of the microbiota on tumor development goes beyond a local effect having a systemic effect. Another aspect of great interest regarding the intestinal microbiota is its relationship with drugs, modifying their activity. There is increasing evidence that the microbiota influences the therapeutic activity and side effects of antineoplastic drugs and also modulates the response of several tumors to antineoplastic therapy through immunological circuits. These data suggest the manipulation of the microbiota as a possible adjuvant to improve oncological treatment. Is it possible to manipulate the microbiota for therapeutic purposes? Full article
(This article belongs to the Special Issue The 25th Anniversary of CIMB: Perspectives in Molecular Biology)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-5
Back to TopTop