cimb-logo

Journal Browser

Journal Browser

Microalga Biotechnology and Applications: Molecular and Cellular Mechanisms

A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Biochemistry, Molecular and Cellular Biology".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 1098

Special Issue Editor


E-Mail Website
Guest Editor
Departamento de Bioquímica y Biología Molecular, Campus de Rabanales y, Campus Internacional de Excelencia Agroalimentario (CeiA3), Edif. Severo Ochoa, Universidad de Córdoba, 14071 Córdoba, Spain
Interests: chlamydomonas; methylobacterium; nitrogen; nitrate; molybdenum; mutualism; nitric oxide; nitrious oxide; microalgae
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Algae and microalgae, spanning both eukaryotic and prokaryotic domains, showcase a remarkable diversity, harboring a plethora of bioactive molecules. Our Special Issue delves deeply into the intricate molecular and cellular mechanisms that underlie the biotechnological potential of microalgae. Through cutting-edge research, we aim to unravel the molecular biology of microalgae, elucidating their physiological processes, metabolic pathways and genetic regulation.

By dissecting the molecular intricacies governing the unique biochemical capabilities of microalgae, such as photosynthesis and bioactive compound synthesis, researchers will provide invaluable insights into their applications across various industries. From biofuel production to pharmaceuticals, cosmetics and wastewater treatment, the versatile applications of microalga biotechnology will be underscored.

We warmly welcome submissions and aim to provide a platform for communication and collaboration among researchers and practitioners in the field. Leveraging molecular and cellular insights, this Special Issue promises to offer a holistic perspective on the biotechnological exploitation of microalgae, fostering invaluable knowledge exchange for all stakeholders. 

Dr. Angel Llamas
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microalgae
  • biotechnology
  • cyanobacteria
  • chlamydomonas
  • cellular stress
  • nutrient limitations
  • molecular mechanisms
  • omics technologies

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

16 pages, 1858 KiB  
Article
Desmodesmus Extract as a Mitochondrion-Targeted Neuroprotective Agent in Parkinson’s Disease: An In Vitro Study
by Muazzez Derya-Andeden, Pinar Altin-Celik, Enver Ersoy Andeden and Hamiyet Donmez-Altuntas
Curr. Issues Mol. Biol. 2025, 47(3), 174; https://doi.org/10.3390/cimb47030174 - 6 Mar 2025
Viewed by 680
Abstract
Parkinson’s disease (PD) is the second most common neurodegenerative disease, and its prevalence is expected to double in the next 30 years. Currently, no effective treatment exists for Parkinson’s disease. Thus, the research has focused on discovering new natural compounds with strong neuroprotective [...] Read more.
Parkinson’s disease (PD) is the second most common neurodegenerative disease, and its prevalence is expected to double in the next 30 years. Currently, no effective treatment exists for Parkinson’s disease. Thus, the research has focused on discovering new natural compounds with strong neuroprotective potential. This study aimed to investigate the effects of the methanol extract of Desmodesmus arthrodesmiformis EM13 (DaMe) on the mitochondrial damage pathway in an in vitro model of PD. The isolate of Desmodesmus arthrodesmiformis EM13 was first grown under appropriate culture conditions, and then the extract (DaMe) was prepared for use in the experiments. The total lipid and protein contents, fatty acid composition, and elemental content of DaMe were subsequently determined. Human SH-SY5Y neuroblastoma cells were pretreated with nontoxic concentrations of DaMe before 6-hydroxydopamine (6-OHDA) toxicity. Pretreatment with DaMe at concentrations of 100, 250, and 500 µg/mL showed a neuroprotective effect on 6-OHDA-induced SH-SY5Y neuroblastoma cells by decreasing the reactive oxygen species (ROS) production, decreasing the total oxidant status (TOS), increasing the total antioxidant capacity (TAC), increasing the mitochondrial membrane potential (ΔΨm), decreasing the oxidative DNA damage, and regulating gene expressions related to PD and apoptosis. Given the results of our study, we suggest that DaMe can be used as a natural source for producing drugs and dietary supplements intended to treat PD. Full article
Show Figures

Graphical abstract

Back to TopTop