Mechanisms and Pathophysiology of Obesity
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 325
Special Issue Editor
Special Issue Information
Dear Colleagues,
Obesity is a chronic, relapsing condition characterized by excess body fat. It occurs when the balance is lost between energy intake vs. expenditure. Obesity is caused by many factors, including genetics, viruses, environment, physical activity and diet, insulin resistance, inflammation, gut microbiome, medications, circadian rhythms, psychological distress and stress, pollution, parental body mass index, maternal smoking, etc. Hormones, growth factors, and organs and tissues regulate the progression of obesity. The molecular mechanisms and pathophysiology of obesity involve a complex interplay of various factors.
There are serious health consequences due to obesity. Excessive fat accumulation not only disrupts the normal function of adipose tissue but also places a burden on organs such as the heart and liver, elevating the risk of multiple chronic diseases. Therefore, research is important to understand the unexplored mechanisms and develop effective interventions to improve health outcomes and digital tools to monitor and provide real-time feedback to help patients.
Dr. Padmamalini Baskaran
Guest Editor
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Keywords
- understanding genetic factors for obesity at the molecular level
- understanding environmental factors for obesity at the molecular level
- contribution of insulin resistance to obesity and ways to combat
- circadian misalignment–molecular level understanding of its contribution to obesity and ways to mitigate it
- effective and individualized obesity treatment strategies for stress
- molecular understanding of the influence of parental obesity on childhood overweight
- molecular mechanisms of maternal smoking on childhood obesity
- therapeutic interventions for obesity through recombinant hormones
- role of gut hormones in the treatment of obesity
- development of new digital tools for weight management interventions
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