Special Issue "Challenges in Children's Medicine Treatments: From Off-Label Use to Extemporaneous Formulations"

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Global and Public Health".

Deadline for manuscript submissions: 25 January 2022.

Special Issue Editors

Prof. Dr. Carlo Giaquinto
E-Mail Website
Guest Editor
Division of Paediatric Infectious Diseases, Department of Women's and Children's Health, University-Hospital of Padua, Via Giustiniani 3, 35128 Padua, Italy
Interests: infectious diseases; clinical research; HIV; antiviral treatment; vaccines
Special Issues and Collections in MDPI journals
Dr. Elisa Barbieri
E-Mail Website
Guest Editor
Division of Paediatric Infectious Diseases, Department of Women's and Children's Health, University-Hospital of Padua, Via Giustiniani 3, 35128 Padua, Italy
Interests: pharmacoepidemiology; antimicrobial stewardship; vaccines; health policy intervention; primary care; real-world data
Dr. Marc Lallemant
E-Mail Website
Guest Editor
Department of Immunology and Infectious Diseases, Programme for HIV Prevention and Treatment (PHPT)/IRD, Boston, MA 02115, USA
Interests: clinical research; paediatrics; HIV

Special Issue Information

Dear Colleagues,

Many medicines of major clinical importance for children are still missing, or have not been readily tested, officially approved for use, or appropriately formulated for children, especially for the very young. To tackle this gap, medicines are often used off-label for an unapproved indication or in an unapproved age group, dosage, or route of administration or prepared extemporaneously either from the active ingredients and excipients or by modifying adult formulations. In the first case the main challenges are dosing, acceptability, and safety, while issues with extemporaneously prepared medicines also include formulation quality, especially chemical and microbiological stability.

With this Special Issue we want to gather evidence on which medicine formulations are not appropriate for children, on the challenges faced by health care professionals and patients when using medicines, and on the solutions that have been found.

In particular, we would like to encourage field practitioners, researchers, and experts to submit manuscripts related to the following topics:

  • Off-label use of medicines;
  • Extemporaneous preparations;
  • Dosing and safety of medicines;
  • Medicine formulations’ acceptability including complexities in using the devices;
  • Usability by caregivers, including complexities in determining the dose.

Prof. Dr. Carlo Giaquinto
Dr. Elisa Barbieri
Dr. Marc Lallemant
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • off-label use
  • pediatric medicines development
  • extemporaneous formulations
  • dosing regimens
  • therapeutic drug monitoring
  • adverse events
  • formulation acceptability
  • medical device use

Published Papers

This special issue is now open for submission.
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