Hypoxic–Ischemic Brain Injury in Newborn: The Present Status and Challenges in the Future
A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Neurology & Neurodevelopmental Disorders".
Deadline for manuscript submissions: 25 January 2026 | Viewed by 11
Special Issue Editor
Interests: neonatal neurology; perinatal brain injury; hypoxic–ischemic injury; stroke; neuroprotection; genetics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hypoxic–ischemic brain injury remains a leading cause of neonatal mortality and long-term neurodevelopmental disabilities, primarily affecting the term-born population, although preterm infants may also be at risk. Despite remarkable advances in perinatal care, the diagnosis and therapy of neonatal brain injury remain a challenge, and therapies are largely supportive. The only established clinical intervention for hypoxic–ischemic brain injury is therapeutic hypothermia demonstrating reductions in risk of death or impairment. However, half of treated infants still suffer from major neurological problems such as cerebral palsy or epilepsy. Furthermore, in preterm infants, therapeutic hypothermia cannot be applied due to its side effects and insufficiency.
This Special Issue critically examines challenges in optimizing treatment and timing, improving access to care in low-resource settings, and addressing long-term outcomes. Additionally, the Issue highlights future directions, including precision medicine approaches, artificial intelligence in early diagnosis, and innovative rehabilitation methods. By integrating multidisciplinary perspectives, this Special Issue aims to bridge the gaps between research and clinical practice, serving as a comprehensive resource for clinicians and researchers and fostering improved outcomes for affected newborns worldwide.
Prof. Dr. Mark Dzietko
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- brain
- neuroprotection
- encephalopathy
- hypoxia ischemia
- stroke
- seizures
- neuromonitoring
- neuro-NICU
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
