AI in Youth Mental Health: From Evidence to Practice

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Mental Health".

Deadline for manuscript submissions: 5 November 2026 | Viewed by 20

Special Issue Editor


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Guest Editor
Department of Psychiatry, University General Hospital of Patras, 26504 Patras, Greece
Interests: pediatric clinical psychology; neuropsychology; cognitive neuroscience; psychopathology; neuroeducation; psychotherapeutic processes; applied psychology
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Special Issue Information

Dear Colleagues,

Mental-health problems among children, adolescents, and young adults have reached unprecedented levels, while specialist services remain unable to meet demand. Artificial-intelligence (AI) tools—chatbots, mobile-health apps, virtual reality, AI-augmented internet-delivered cognitive behavioural therapy, and machine-learning decision-support systems—are being deployed rapidly as scalable complements to traditional care, yet the evidence base remains fragmented across single modalities, single conditions, or single age bands. This Special Issue assembles cross-modality, cross-condition contributions that move the field beyond whether AI mental-health interventions work on average toward the more clinically-useful questions of for whom, which AI modality, at what dose, and under what safeguards they work best. We welcome rigorously-conducted systematic reviews, meta-analyses, prospective trials, individual-participant-data analyses, and implementation-science studies aligned with PRISMA 2020, CONSORT-AI, TRIPOD+AI, and GRADE. Methodological-innovation papers (extraction-integrity auditing, AI-specific risk-of-bias domains, fairness audits) and ethics-, equity-, and lived-experience–focused contributions are particularly encouraged. Together, the collection will deliver a citable evidence base to inform clinical practice, policy, and the next generation of paediatric digital-mental-health research.

Dr. Evgenia Gkintoni
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • artificial intelligence
  • digital mental health
  • children
  • adolescents
  • young adults
  • chatbots
  • mobile health
  • virtual reality
  • machine learning
  • internet-delivered cognitive behavioural therapy
  • depression
  • anxiety
  • suicide and self-harm

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Published Papers

This special issue is now open for submission.
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