From Molecular Mechanisms to Treatment Progress of Ovarian Cancer
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Reproductive Cells and Development".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 842
Special Issue Editor
2. Pathology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt
Interests: sarcoma; ovarian cancers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ovarian cancer remains one of the deadliest gynecologic malignancies worldwide, largely due to vague symptoms that often lead to late-stage diagnosis, high recurrence rates, and the development of drug resistance. Understanding the molecular mechanisms that drive ovarian cancer progression has become pivotal for improving diagnosis, prognostication, and treatment strategies. This Special Issue aims to highlight the latest advances in elucidating the molecular underpinnings of ovarian cancer, including genetic and epigenetic alterations, signaling pathway dysregulation, and tumor microenvironment interactions. We also focus on therapeutic opportunities, encompassing targeted therapies, immunotherapies, and combination strategies designed to overcome treatment resistance. Additionally, the identification of novel biomarkers for early detection, disease monitoring, and therapeutic response prediction is emphasized. Contributions may include original research, comprehensive reviews, and perspectives on the development of preclinical models, including patient-derived xenografts and organoids, which are crucial for translational research and drug development. By integrating insights from molecular mechanisms with advances in therapeutic interventions, this Special Issue seeks to provide a comprehensive overview of current progress and future directions in ovarian cancer research. We invite manuscripts that explore innovative approaches to decipher molecular pathways, address challenges in treatment resistance, and propose potential strategies for improving patient outcomes.
Dr. Amal M. El-Naggar
Guest Editor
Manuscript Submission Information
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Keywords
- ovarian cancer
- molecular mechanisms
- therapeutic targets
- drug resistance
- biomarkers
- preclinical models
- targeted therapy
- immunotherapy
- tumor microenvironment
- translational research
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