Autophagy, Mitophagy and Disease
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Autophagy".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 14263
Special Issue Editor
Interests: cellular stress pathways; autophagy; mitochondrial homeostasis; neurodegeneration; metabolic diseases; obesity; inflammation; infection
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Since the introduction of the term ‘autophagy’ for all processes that deliver cytosolic material to the lysosome or vacuole for degradation by Christian de Duve in the 1960s and the identification of the genes that encode for the execution machinery by Yoshinori Ohsumi in the 1980s, this process has taken center stage in basic and translational research. The well-established mechanistic contribution of autophagy (and its selective subtypes, e.g., mitophagy) to human diseases such as neurodegeneration, cancer, and metabolic syndrome has spawned the quest for tailored drugs that target specific regulatory proteins or pathways involved in pathogenic events. In this Special Issue of Cells, I cordially invite you to contribute reviews, comments, or original research articles on various aspects related to the theme of “Autophagy, Mitophagy and Disease”. Articles addressing cellular, biochemical, mechanistic, translational, clinical, or general aspects of autophagy and its selective forms are highly welcome. Relevant topics include but are not limited to:
- Molecular mechanisms of autophagy and mitophagy
- Mitochondrial homeostasis
- Organelle turnover
- Selective autophagy pathways
- Clinical relevance of autophagy and mitophagy
- Molecular mechanisms of regulation and execution
- Chronic inflammation
- Cancer
- Neurodegeneration
- Mood disorders
- Infection
- Intracellular pathogens
- Metabolic syndrome
- Autophagic cell death
- Stem cell biology
- Aging
- Drugs targeting autophagy pathways.
This may also be a great opportunity for early-stage researchers to present their data or introduce their view on selected aspects of this fascinating cellular pathway. As a plus, this Special Issue will be made available in printed book format if we jointly manage to publish more than 10 papers.
I look forward to your ideas and contributions!
Dr. Andreas Till
Guest Editor
Manuscript Submission Information
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