Special Issue "Hallmarks of Parkinson’s Disease"
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 28 February 2021.
Interests: Parkinson’s disease; brain tumors; transcription; autophagy; cell death; unfolded protein response
Parkinson’s disease (PD) is a movement disorder characterized by the degeneration of dopaminergic neurons. PD is the second cause of motor disability in aged populations, and it affects one person out of 1000. Thus, given the health and economic impacts associated with the increase of PD prevalence in aging populations, the decryptage of the molecular cascades responsible for the etiology of the disease and/or contributing to its progression is crucial. During the last few decades the huge effort of the scientifc community to gain insight into the pathophysiology of PD has culminated in the idenfication of multiple interconnected disfonctional processes. These frequent dysfunctions have been recently named “PD hallmarks” by Antonny and colleagues. This categorization, probably inspired by the seminal work of Hanahan and Weinberg concerning cancer hallmarks, also pinpoints the fact that degenerating neurons share several cellular defective processes.
This Special Issue offers an open access forum that gathers a collection of review articles aiming to update the current knowledge on PD pathogenesis. Suggested potential topics include, but are not restricted to, PD hallmarks, e.g., mitochondrial dysfunction, lysosomal and proteasome failure, neuroinflamation, protein misfolding, apoptosis, calcium inbalance, synaptic dysfunction, oxidative stress, mitophagy, propagation, and spreading.
Dr. Cristine Alves Da Costa
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Parkinson’s disease
- cellular common dysfunctional processes
- animal models